Clinical differences between elderly and non-elderly patients with COVID-19

dc.contributor.authorUcsular, Fatma Demirci
dc.contributor.authorKaradeniz, Gulistan
dc.contributor.authorPolat, Gulru
dc.contributor.authorAyrancı, Aysu
dc.contributor.authorYalniz, Enver
dc.contributor.authorKazankaya, Fatmanur
dc.contributor.authorGuldaval, Filiz
dc.date.accessioned2023-03-22T19:47:22Z
dc.date.available2023-03-22T19:47:22Z
dc.date.issued2022
dc.departmentBelirleneceken_US
dc.description.abstractOBJECTIVE: Comorbidity frequency and mortality rates are higher in elderly patients with COVID-19. The disease is also more severe in elderly patients. This study aims to examine the characteristics of the COVID-19 disease, severity, comorbidities, and mortality rates in elderly patients by comparing them with nonelderly patients. MATERIAL AND METHODS: This study was designed as a retrospective study. 469 patients who were followed up in outpatient, inpatient, and intensive care units with the diagnosis of COVID-19 between March 11, 2020, and June 01, 2020, were retrospectively included in the study. Patients were divided into two groups who were >= 65 years named as the elderly group and <65 years referred to as nonelderly. Survival data was generated from the death notification system on August 02, 2020. RESULTS: A total of 469 patients including elderly(n=101) and nonelderly(n=368) were included in the study retrospectively. The incidence of severe pneumonia(31%/12.6%) and critical illness(16%/5.8%), comorbidity (85%/37.2%) and hospitalization time(8/5 days) were significantly higher in the elderly group(p<0.05). 23 (22.8%) of elderly patients and 27(7.3%) of nonelderly patients died (p=0.000). Mortality was found to be 3.5 times higher than in the non-elderly group. The expected survival time was 145.85 days(CI 95%:133-158.66) in the elderly patients and 170.36 days(CI 95%:166-174.6) in the nonelderly patients (p<0.000). In ROC analysis, the sensitivity of age was 86%(73.3-94.2), specificity was 66.83%(62.1-71.3), and the cut-off>56 (AUC:0.775; p <0.001) in predicting mortality. CONCLUSION: Mortality is high, comorbidities are more frequent, and the disease is more severe in elderly patients with COVID-19. Age above 56 can be used as a cut-off to predict mortality.en_US
dc.identifier.doi10.5152/TurkThoracJ.2022.21288
dc.identifier.endpage245en_US
dc.identifier.issn2149-2530
dc.identifier.issue3en_US
dc.identifier.pmid35579231en_US
dc.identifier.scopus2-s2.0-85130986471en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage238en_US
dc.identifier.urihttps://doi.org/10.5152/TurkThoracJ.2022.21288
dc.identifier.urihttps://hdl.handle.net/20.500.14034/660
dc.identifier.volume23en_US
dc.identifier.wosWOS:000841463900007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.journalTurkish Thoracic Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectComorbidityen_US
dc.subjectCOVID-19en_US
dc.subjectelderly patienten_US
dc.subjectmortalityen_US
dc.titleClinical differences between elderly and non-elderly patients with COVID-19en_US
dc.typeArticleen_US

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