A comparison of the clinical features of molar pregnancy in adolescents and adults

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dc.authoridyildirim karaca, suna/0000-0001-6633-0342
dc.contributor.authorOzer, Mehmet
dc.contributor.authorOzer, Pinar Tugce
dc.contributor.authorKaraca, Ibrahim
dc.contributor.authorKaraca, Suna
dc.contributor.authorIleri, Alper
dc.contributor.authorBudak, Adnan
dc.date.accessioned2025-03-20T09:50:44Z
dc.date.available2025-03-20T09:50:44Z
dc.date.issued2024
dc.departmentİzmir Bakırçay Üniversitesi
dc.description.abstractObjective: To compare the age -specific clinical features of molar pregnancy and to describe the risk factors associated with this situation. Method : This retrospective case -control study was conducted at the Department of Obstetrics and Gynecology. Tepecik Education and Research Hospital, Izmir, Turkey. The participants included both adolescents (<= 19 years) and adults with histologically confirmed hydatidiform moles in our institution between January 2015 and January 2022. The interventions and main outcome measures of this study involved evaluating the clinical and ultrasonographic features, as well as the risk factors, associated with molar pregnancies in adolescents. Results : This study of 137 patients with molar pregnancy found that adults had a higher incidence of partial molar pregnancy (20 patients versus seven patients) and lower beta-hCG levels than adolescents (176.890.71 mIU/ml versus 253.734.47 mIU/ml). Adolescents had a higher likelihood of hyperthyroidism (25.4% versus 9.2%). bleeding on admission (4.2% versus 1.51%),. longer hospital stays (5.44 +/- 2.73 days versus 3.59 +/- 3.08 days). Higher rates of uterine enlargement and postoperative bleeding (15.5% versus 1.5%). Adolescents also required more analgesia (97% versus 89.4%). Conclusions: A dolescents with Gestational trophoblastic diseases (GTD) may present with more severe symptoms compared to adults, which can lead to delayed diagnosis and treatment. Further research is needed to better understand the underlying mechanisms and risk factors for GTDs in this population. Increased awareness and education can help improve recognition and management of GTDs in adolescents and improve their overall health outcomes.
dc.identifier.doi10.12669/pjms.40.5.8383
dc.identifier.endpage850
dc.identifier.issn1682-024X
dc.identifier.issn1681-715X
dc.identifier.issue5
dc.identifier.pmid38827845
dc.identifier.scopus2-s2.0-85190994448
dc.identifier.scopusqualityQ1
dc.identifier.startpage846
dc.identifier.urihttps://doi.org/10.12669/pjms.40.5.8383
dc.identifier.urihttps://hdl.handle.net/20.500.14034/2279
dc.identifier.volume40
dc.identifier.wosWOS:001222057600021
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherProfessional Medical Publications
dc.relation.ispartofPakistan Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250319
dc.subjectGestational trophoblastic diseases
dc.subjectHydatidiform mole
dc.subjectVaginal bleeding
dc.subjectVisual analogue scores
dc.titleA comparison of the clinical features of molar pregnancy in adolescents and adults
dc.typeArticle

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