Evaluation of bleeding rate and time in therapeutic range in patients using warfarin before and during the COVID-19 pandemic-warfarin treatment in COVID-19

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dc.authoridemren, volkan / 0000-0002-7652-1123
dc.authorscopusid56365496200
dc.authorscopusid56157249300
dc.authorscopusid56054200300
dc.authorscopusid55993139900
dc.authorwosidEMREN, Zeynep YAPAN/AAV-8842-2021
dc.contributor.authorEmren, Zeynep Yapan
dc.contributor.authorŞenöz, Oktay
dc.contributor.authorErsecgin, Ahmet
dc.contributor.authorEmren, Sadık Volkan
dc.date.accessioned2022-02-15T16:57:39Z
dc.date.available2022-02-15T16:57:39Z
dc.date.issued2021
dc.departmentBakırçay Üniversitesien_US
dc.description.abstractThe treatment process of patients using warfarin is expected to be hindered during the COVID-19 pandemic. Therefore we investigated whether the time in therapeutic range (TTR) and bleeding complications were affected during the COVID-19 pandemic. 355 patients using warfarin were included between March 2019 to March 2021. Demographic parameters, INR (international normalized ratio), and bleeding rates were recorded retrospectively. The TTR value was calculated using Rosendaal's method. The mean age of the patients was 61 +/- 12 years and 55% of them were female. The mean TTR value during the COVID-19 pandemic was lower than the pre-COVID-19 period (56 +/- 21 vs 68 +/- 21, P < 0.001). Among the patients, 41% had a lack of outpatient INR control. During the COVID-19 pandemic, 71 (20%) patients using VKA suffered bleeding. Among patients with bleeding, approximately 60% did not seek medical help and 6% of patients performed self-reduction of the VKA dose. During the COVID-19 pandemic, TTR values have decreased with the lack of monitoring. Furthermore, the majority of patients did not seek medical help even in case of bleeding.en_US
dc.identifier.doi10.1177/10760296211021495
dc.identifier.issn1076-0296
dc.identifier.issn1938-2723
dc.identifier.pmid34142564en_US
dc.identifier.scopus2-s2.0-85108158368en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1177/10760296211021495
dc.identifier.urihttps://hdl.handle.net/20.500.14034/235
dc.identifier.volume27en_US
dc.identifier.wosWOS:000688043200001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.journalClinical And Applied Thrombosis-Hemostasisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectwarfarinen_US
dc.subjectprothrombin timeen_US
dc.subjecttime in therapeutic rangeen_US
dc.subjectSARS-Cov2en_US
dc.subjectCOVID-19en_US
dc.subjectAtrial-Fibrillationen_US
dc.subjectGuidelinesen_US
dc.subjectDefinitionen_US
dc.subjectManagementen_US
dc.subjectEscen_US
dc.titleEvaluation of bleeding rate and time in therapeutic range in patients using warfarin before and during the COVID-19 pandemic-warfarin treatment in COVID-19en_US
dc.typeArticleen_US

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