The relationship between good collateral development and magnesium/phosphate ratios in chronic total occlusion

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dc.contributor.authorKış, Mehmet
dc.contributor.authorŞenöz, Oktay
dc.contributor.authorGüzel, Tuncay
dc.date.accessioned2023-03-22T19:48:14Z
dc.date.available2023-03-22T19:48:14Z
dc.date.issued2022
dc.departmentBelirleneceken_US
dc.description.abstractObjective: Coronary collateral formation can be triggered by many acquired factors such as ischemia and growth factors, which ultimately manifests as differences in the quality of the coronary collateral circulation (CCC) in patients. Low magnesium (Mg) levels can increase endothelial cell dysfunction and potentially increase the risk of thrombosis and atherosclerosis. However, it has been reported that high serum phosphate (P) levels are correlated with the development of atherosclerosis and mortality. In this article, we aimed to reveal the relationship between CCC quality and Mg/P ratio in chronic total occlusion (CTO). Methods: A total of 269 patients with detected CTO in coronary angiography between March 2014 and June 2018 were included in the study. The patients were divided into two groups as group I (127 patients) and group II (142 patients) according to the Rentrop classification. The study is a retrospective, observational study. Results: In the multivariable regression analysis; smoking (p=0.004), triglyceride (p<0.001) and Mg/P ratio (p<0.001) parameters were independent predictors affecting CCC in CTO. Mg/P value was statistically lower in the group I (0.49±0.17) than group II (0.62±0.12) (p<0.001). The ideal Mg/P cut-off value was 0.56 that calculated by the Youden index had 69% sensitivity, and 64% specificity for collateral development of CTO. Conclusion: Mg/P is a parameter that affects coronary collateral development. High Mg/P ratio level is associated with good collateral development in patients who had CTO.en_US
dc.identifier.doi10.53446/actamednicomedia.1147651
dc.identifier.endpage130en_US
dc.identifier.issn2717-8994
dc.identifier.issue3en_US
dc.identifier.startpage126en_US
dc.identifier.trdizinid1142009en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14034/1028
dc.identifier.urihttps://doi.org/10.53446/actamednicomedia.1147651
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1142009
dc.identifier.volume5en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.journalActa Medica Nicomediaen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCoronary artery diseaseen_US
dc.subjectchronic total occlusionen_US
dc.subjectMg/P ratioen_US
dc.subjectcollateral development Koroner arter hastalığıen_US
dc.subjectkronik total oklüzyonen_US
dc.subjectMg/P oranıen_US
dc.subjectkollateral gelişimen_US
dc.titleThe relationship between good collateral development and magnesium/phosphate ratios in chronic total occlusionen_US
dc.typeArticleen_US

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