Evaluation of the Relationship between Simple Hemogram Indexes and Disease Severity Scores in Pediatric Familial Mediterranean Fever

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dc.authorscopusid57112529800
dc.authorscopusid7006604555
dc.contributor.authorGüngörer Vildan
dc.contributor.authorArslan Şükrü
dc.date.accessioned2023-03-22T19:47:51Z
dc.date.available2023-03-22T19:47:51Z
dc.date.issued2022
dc.departmentBelirleneceken_US
dc.description.abstractAim: In recent years, it has been seen that simple complete blood count (CBC) parameters can be used to show subclinical inflammation in patients with familial Mediterranean fever (FMF). The aim of this study is to determine whether there is a difference in CBC parameters among FMF patient groups divided according to disease severity scores. Material and Methods: FMF patients followed up in our clinic between 2016 and 2019, were reviewed for medical records. They were divided into three groups as those with mild, moderate, and severe diseases according to the disease severity scoring systems by Pras et al., Mor et al., and International Severity Score of FMF (ISSF). Red cell distribution width (RDW), platelet, neutrophil, lymphocyte, RDW-platelet ratio (RPR), platelet-lymphocyte ratio (PLR), and neutrophil-lymphocyte ratio (NLR) of the patients were compared among the groups. Results: According to the scoring system of Pras et al., lymphocyte value was found significantly higher in the group with severe disease compared to the groups with mild and moderate diseases (p=0.031). PLR was significantly lower in the group with severe disease compared to moderate diseases according to the scoring system of Mor et al (p=0.008). According to ISSF, there was no difference among the groups in terms of CBC parameters. Conclusion: Different results were obtained according to all three scoring systems. Since the ISSF is the most common and suitable system for use in FMF patients, we can conclude that there is no relationship between disease severity and RDW, RPR, NLR and PLR. © 2022, Duzce University Medical School. All rights reserved.en_US
dc.description.sponsorshipThe authors thank Enago – https://www.enago.com.tr/ceviri/ for their assistance in manuscript translation and editing. The authors were working at Selçuk University Faculty of Medicine at the data collection phase of the study.en_US
dc.identifier.doi10.18678/dtfd.1037824
dc.identifier.endpage25en_US
dc.identifier.issn1307671X
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85130765659en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage18en_US
dc.identifier.trdizinid1070933en_US
dc.identifier.urihttps://doi.org/10.18678/dtfd.1037824
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1070933
dc.identifier.urihttps://hdl.handle.net/20.500.14034/889
dc.identifier.volume24en_US
dc.identifier.wosWOS:001410232300003
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherDuzce University Medical Schoolen_US
dc.relation.journalDuzce Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectComplete blood counten_US
dc.subjectdisease severity indexen_US
dc.subjectfamilial Mediterranean feveren_US
dc.subjectC reactive proteinen_US
dc.subjectadolescenten_US
dc.subjectArticleen_US
dc.subjectblood cell counten_US
dc.subjectbody massen_US
dc.subjectchilden_US
dc.subjectcontrolled studyen_US
dc.subjectdisease severityen_US
dc.subjectdisease severity assessmenten_US
dc.subjecterythrocyte sedimentation rateen_US
dc.subjectfamilial Mediterranean feveren_US
dc.subjectfemaleen_US
dc.subjectfollow upen_US
dc.subjectinfanten_US
dc.subjectinflammationen_US
dc.subjectInternational Severity Score FMFen_US
dc.subjectleukocyte counten_US
dc.subjectlymphocyte counten_US
dc.subjectmajor clinical studyen_US
dc.subjectmaleen_US
dc.subjectneutrophil counten_US
dc.subjectneutrophil lymphocyte ratioen_US
dc.subjectpediatric patienten_US
dc.subjectplatelet counten_US
dc.subjectplatelet lymphocyte ratioen_US
dc.subjectpreschool childen_US
dc.subjectred blood cell distribution widthen_US
dc.subjectschool childen_US
dc.subjectscoring systemen_US
dc.titleEvaluation of the Relationship between Simple Hemogram Indexes and Disease Severity Scores in Pediatric Familial Mediterranean Feveren_US
dc.title.alternativePediatrik Ailevi Akdeniz Ateşinde basit hemogram indeksleri ile hastalık şiddet skorları arasındaki ilişkinin değerlendirilmesien_US
dc.typeArticleen_US

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