Hemoglobin A1c Level is Associated with Lymphovascular Space Invasion in Diabetic Endometrial Cancer Patients

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dc.contributor.authorŞenkaya, Ayşe Rabia
dc.contributor.authorKantarcı, Sercan
dc.contributor.authorKaraca, Suna Yıldırım
dc.contributor.authorSanci, Muzaffer
dc.date.accessioned2025-03-20T09:41:27Z
dc.date.available2025-03-20T09:41:27Z
dc.date.issued2024
dc.departmentİzmir Bakırçay Üniversitesi
dc.description.abstractOBJECTIVE: Our aim in this study is to examine the relationship of hemoglobin A1c (HbA1c) and fast- ing glucose with the stage, grade, and histological type of cancer and its value in predicting the prog- nosis of endometrial cancer in diabetic endometrial cancer patients. STUDY DESIGN: The data of 138 endometrial cancer patients with diabetes who met the study criteria were analyzed. Hemoglobin A1c levels and fasting glucose were compared with cancer stage, grade, histological type, lymphovascular invasion, chemotherapy, and radiotherapy data. RESULTS: A statistically significant difference was found between the groups in terms of HbA1c values only according to the lymphovascular invasion ( p=0.02). While there was no significant correlation be- tween endometrial thickness and HbA1c, a low positive correlation was found between the fasting glu- cose value (r=0.191, p=0.025) CONCLUSIONS: The higher rate of lymphovascular invasion in patients with high HbA1c values alone is insufficient in determining the prognosis when other parameters are considered.
dc.identifier.doi10.21613/GORM.2023.1386
dc.identifier.endpage54
dc.identifier.issn1300-4751
dc.identifier.issn2602-4918
dc.identifier.issue1
dc.identifier.startpage50
dc.identifier.trdizinid1278849
dc.identifier.urihttps://doi.org/10.21613/GORM.2023.1386
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1278849
dc.identifier.urihttps://hdl.handle.net/20.500.14034/1975
dc.identifier.volume30
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofGORM:Gynecology Obstetrics & Reproductive Medicine
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TR_20250319
dc.subjectDiabetes mellitus
dc.subjectEndometrial neoplasms
dc.subjectGlycated hemoglobin A
dc.titleHemoglobin A1c Level is Associated with Lymphovascular Space Invasion in Diabetic Endometrial Cancer Patients
dc.typeArticle

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