Hemoglobin A1c Level is Associated with Lymphovascular Space Invasion in Diabetic Endometrial Cancer Patients
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Dosyalar
Tarih
2024
Dergi Başlığı
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
OBJECTIVE: Our aim in this study is to examine the relationship of hemoglobin A1c (HbA1c) and fast- ing glucose with the stage, grade, and histological type of cancer and its value in predicting the prog- nosis of endometrial cancer in diabetic endometrial cancer patients. STUDY DESIGN: The data of 138 endometrial cancer patients with diabetes who met the study criteria were analyzed. Hemoglobin A1c levels and fasting glucose were compared with cancer stage, grade, histological type, lymphovascular invasion, chemotherapy, and radiotherapy data. RESULTS: A statistically significant difference was found between the groups in terms of HbA1c values only according to the lymphovascular invasion ( p=0.02). While there was no significant correlation be- tween endometrial thickness and HbA1c, a low positive correlation was found between the fasting glu- cose value (r=0.191, p=0.025) CONCLUSIONS: The higher rate of lymphovascular invasion in patients with high HbA1c values alone is insufficient in determining the prognosis when other parameters are considered.
Açıklama
Anahtar Kelimeler
Diabetes mellitus, Endometrial neoplasms, Glycated hemoglobin A
