Sit-to-stand test in children with bronchiectasis: Does it measure functional exercise capacity?

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dc.authoridGurses, H. Nilgun / 0000-0002-5846-6781
dc.authoridUcgun, Hikmet / 0000-0002-7211-1805
dc.authoridZeren, Melih / 0000-0002-9749-315X
dc.authoridDENIZOGLU KULLI, Hilal / 0000-0002-8003-4440
dc.authorscopusid57192204790
dc.authorscopusid7006651111
dc.authorscopusid57200518528
dc.authorscopusid57218882596
dc.authorscopusid15757040700
dc.authorwosidGurses, H. Nilgun/AAD-3070-2020
dc.authorwosidUcgun, Hikmet/AAC-5606-2020
dc.contributor.authorZeren, Melih
dc.contributor.authorGürses, Hülya Nilgün
dc.contributor.authorKulli, Hilal Denizoğlu
dc.contributor.authorÜçgün, Hikmet
dc.contributor.authorÇakır, Erkan
dc.date.accessioned2022-02-15T16:59:08Z
dc.date.available2022-02-15T16:59:08Z
dc.date.issued2020
dc.departmentBakırçay Üniversitesien_US
dc.description.abstractBackground: Similar to six-minute walk test (6MWT), sit-to-stand test (STST) is a self-paced test which elicits sub-maximal effort; therefore, it is suggested as an alternative measurement for functional exercise capacity in various pulmonary conditions including COPD and cystic fibrosis. We aimed to investigate the association between 30-second STST (30s-STST) and 6MWT in both children with bronchiectasis (BE) and their healthy counterparts, as well as exploring cardiorespiratory burden and discriminative properties of both tests. Methods: Sixty children (6 to 18-year-old) diagnosed with non-cystic fibrosis BE and 20 age-matched healthy controls were included. Both groups performed 30s-STST and 6MWT. Test results, and heart rate, SpO(2) and dyspnea responses to tests were recorded. Results: Univariate analysis revealed that 30s-STST was able to explain 52% of variance in 6MWT (r = 0.718, p<0.001) in BE group, whereas 20% of variance in healthy controls (r = 0.453, p = 0.045). 6MWT elicited higher changes in heart rate and dyspnea level compared to 30s-STST, indicating it was more physically demanding. Both 30s-STST (21.65 +/- 5.28 vs 26.55 +/- 3.56 repetitions) and 6MWT (538 +/- 85 vs 596 +/- 54 m) were significantly lower in BE group compared to healthy controls (p<0.01). Receiver operating characteristic (ROC) curve analysis revealed an area under the ROC curve (UAC) of 0.765 for 30s-STST and 0.693 for 6MWT in identifying the individuals with or without BE (p<0.05). Comparison between AUCs of 30s-STST and 6MWT yielded no significant difference (p = 0.466), indicating both tests had similar discriminative properties. Conclusions: 30s-STST is found to be a valid alternative measurement for functional exercise capacity in chil-dren with BE. (c) 2020 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.hrtlng.2020.09.017
dc.identifier.endpage802en_US
dc.identifier.issn0147-9563
dc.identifier.issn1527-3288
dc.identifier.issue6en_US
dc.identifier.pmid33010517en_US
dc.identifier.scopus2-s2.0-85091799032en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage796en_US
dc.identifier.urihttps://doi.org/10.1016/j.hrtlng.2020.09.017
dc.identifier.urihttps://hdl.handle.net/20.500.14034/519
dc.identifier.volume49en_US
dc.identifier.wosWOS:000594532000026en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMosby-Elsevieren_US
dc.relation.journalHeart & Lungen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBronchiectasisen_US
dc.subjectChildrenen_US
dc.subjectFunctional exercise capacityen_US
dc.subjectPhysical performanceen_US
dc.subjectSit-to-stand testen_US
dc.subjectSix-minute walk testen_US
dc.subjectValidityen_US
dc.subjectField Walking Testsen_US
dc.subjectCystic-Fibrosisen_US
dc.subjectDeterminantsen_US
dc.subjectPerformanceen_US
dc.subjectToleranceen_US
dc.subjectStatementen_US
dc.subjectPeopleen_US
dc.subjectCopden_US
dc.titleSit-to-stand test in children with bronchiectasis: Does it measure functional exercise capacity?en_US
dc.typeArticleen_US

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