Is chronic respiratory disease a possible risk factor in acute pulmonary thromboembolism?

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Objective: Although we frequently encounter pulmonary thromboembolism (PTE) in patients with chronic respiratory disease in our daily practice, only the presence of respiratory failure is stated as a risk factor in the guideline. In our study, it was aimed to investigate the frequency of acquired risk factors, especially chronic respiratory diseases, in acute PTE. Material and Methods: Our study was designed as a single-center observational descriptive study. Patients hospitalized with the diagnosis of acute PTE in our hospital were evaluated between August 01, 2016 and August 01, 2020. Results: A total of 157 patients were included in our study. The most common acquired risk factors were; being 65 years and older (n=80, 51%), arterial hypertension (n=65, 42.4%), obesity (n=35, 22.3%) and chronic respiratory disease (n=30, %19.1). No ac quired risk factor was found in 31 patients (19.2%). Chronic obstructive lung disease (n=22, 73.3%) was the most common disease among chronic respiratory diseases. Other respiratory diseases were interstitial lung disease (n=5, 16.7%), obstructive sleep apnea syndrome (n=2, 6.7%), and asthma (n=1, 3.3%). The presence of chronic respi ratory disease was significantly higher in men, patients aged 65 and over, and smokers. Conclusion: The frequency of PTE risk factors varies according to countries and socioe conomic level. Our data showed that chronic respiratory disease is more common in PTE patients than many diseases or conditions that are currently considered as risk factors.

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