Investigation of left ventricular systolic and diastolic functions before and after levosimendan administration in patients with heart failure
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Tarih
2021
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info:eu-repo/semantics/openAccess
Özet
Background: we aimed to investigate effect of levosimendan treatment on left ventricle systolic and diastolic parameters with transthoracic echocardiography in patients with heart failure Method: Patients over 18 years old with lower than %35 of ejection fraction and New York Heart Association (NYHA) class III-IV were included. Left ventricle systolic and diastolic parameters before and after levosimendan treatment were compared. Approval was obtained from the local ethics committee of Celal Bayar University Medical Faculty for our study. Results: With levosimendan treatment; E/A ratio(2,25±0,76 vs 1,67±0,75 , p:0,03 ) and E/E’ ratio (23,03±13,60 vs 15,96±8,43 , p:0,01) decreased significantly. Furthermore there was an increase in ejection fraction(20,60±5,65 vs 27,00±7,11 , p:0,01) and A velocity( 0,45±0,14 vs 0,61±0,30 , p:0,03). Conclusion: Levosimendan treatment has an acute favoruble effect in ejection fraction and diyastolic mitral inflow parameters that showed ventricle overload
