The Effect of Obturator Nerve Blockade on Oncological Outcomes of Patients with Lateral Wall Localized Non-Muscle Invasive Bladder Cancer

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dc.authoridCaglayan, Alper/0000-0001-6884-489X
dc.authoridAygun, Hakan/0000-0002-6152-0857
dc.authorwosidCaglayan, Alper/AAC-9373-2022
dc.contributor.authorHorsanali, Mustafa Ozan
dc.contributor.authorEren, Hueseyin
dc.contributor.authorDil, Eyuep
dc.contributor.authorCaglayan, Alper
dc.contributor.authorErdogan, Oezguer
dc.contributor.authorKaraarslan, Sermin
dc.contributor.authorAyguen, Hakan
dc.date.accessioned2024-03-09T18:48:49Z
dc.date.available2024-03-09T18:48:49Z
dc.date.issued2023
dc.departmentİzmir Bakırçay Üniversitesien_US
dc.description.abstractObjective: To investigate the effect of obturator nerve blockade on oncological outcomes of patients with a diagnosis of lateral wall localized non -muscle invasive bladder cancer.Materials and Methods: One hundred six patients diagnosed with lateral wall localized non-invasive bladder cancer were evaluated between January 2015 and March 2020 in this retrospective, cross-sectional observational study. The patients were divided into two groups: patients receiving only spinal anesthesia and those receiving spinal anesthesia combined with ultrasound-guided obturator nerve blockade. Oncological outcomes of the groups were compared statistically.Results: We observed recurrent tumors in 25 patients (45.5%) in Group 1 and 11 patients (21.6%) in Group 2. Additionally, we observed tumor progression in eight patients (14.5%) in Group 1 and two patients (3.9%) in Group 2. We observed statistical significance in differences between groups regarding tumor size, recurrence rate, adequate muscle tissue sampling, ability for complete resection, and persistent obturator reflex. The efficacy rate of obturator blockade was 92.1% in Group 2. One-year recurrence-free survival (RFS) was 98.0% and 5-year RFS was 23.5% for Group 1, while for Group 2, they were 97.4% and 57.2%, respectively. Conclusion: The obturator reflex is a common and challenging reflex that may cause major complications and result in unintended consequences, such as incomplete resection or tumor recurrence with transurethral resection of bladder tumors. In this study, we demonstrated that combining spinal anesthesia with obturator nerve blockade for lateral wall localized non-muscle invasive bladder cancer may prevent tumor recurrence and reduce peroperative complications.en_US
dc.identifier.doi10.4274/jus.galenos.2023.2022.0074
dc.identifier.endpage205en_US
dc.identifier.issn2148-9580
dc.identifier.issue3en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage199en_US
dc.identifier.urihttps://doi.org/10.4274/jus.galenos.2023.2022.0074
dc.identifier.urihttps://hdl.handle.net/20.500.14034/1495
dc.identifier.volume10en_US
dc.identifier.wosWOS:001144161000010en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofJournal of Urological Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBladder Cancer; Non-Muscle Invasive Bladder Cancer; Obturator Nerve Blockade; Adductor Contraction; Bladder Perforation; And Nerve Blocken_US
dc.titleThe Effect of Obturator Nerve Blockade on Oncological Outcomes of Patients with Lateral Wall Localized Non-Muscle Invasive Bladder Canceren_US
dc.typeArticleen_US

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