Evaluation of immunization status in patients with cerebral palsy: a multicenter CP-VACC study

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dc.authoridOlgac Dundar, Nihal / 0000-0002-5902-3501
dc.authoridBozkaya Yilmaz, Sema / 0000-0002-5389-5616
dc.authorscopusid57209256022
dc.authorscopusid36994455700
dc.authorscopusid25623200200
dc.authorscopusid53879580300
dc.authorscopusid6602402327
dc.authorscopusid57191406289
dc.authorscopusid13205268800
dc.contributor.authorBozkaya Yılmaz, Sema
dc.contributor.authorKaradağ Öncel, Eda
dc.contributor.authorOlgac-Dündar, Nihal
dc.contributor.authorGencpinar, Pınar
dc.contributor.authorSarioğlu, Berrak
dc.contributor.authorArican, Pınar
dc.contributor.authorÇavusoğlu, Dilek
dc.date.accessioned2022-02-15T16:57:26Z
dc.date.available2022-02-15T16:57:26Z
dc.date.issued2021
dc.departmentBakırçay Üniversitesien_US
dc.description.abstractChildren with chronic neurological diseases, including cerebral palsy (CP), are especially susceptible to vaccine-preventable infections and face an increased risk of severe respiratory infections and decompensation of their disease. This study aims to examine age-appropriate immunization status and related factors in the CP population of our country. This cross-sectional prospective multicentered survey study included 18 pediatric neurology clinics around Turkey, wherein outpatient children with CP were included in the study. Data on patient and CP characteristics, concomitant disorders, vaccination status included in the National Immunization Program (NIP), administration, and influenza vaccine recommendation were collected at a single visit. A total of 1194 patients were enrolled. Regarding immunization records, the most frequently administrated and schedule completed vaccines were BCG (90.8%), hepatitis B (88.9%), and oral poliovirus vaccine (88.5%). MMR was administered to 77.3%, and DTaP-IPV-HiB was administered to 60.5% of patients. For the pneumococcal vaccines, 54.1% of children received PCV in the scope of the NIP, and 15.2% of children were not fully vaccinated for their age. The influenza vaccine was administered only to 3.4% of the patients at any time and was never recommended to 1122 parents (93.9%). In the patients with severe (grades 4 and 5) motor dysfunction, the frequency of incomplete/none vaccination of hepatitis B, BCG, DTaP-IPV-HiB, OPV, and MMR was statistically more common than mild to moderate (grades 1-3) motor dysfunction (p = 0.003, p < 0.001, p < 0.001, p < 0.00, and p < 0.001, respectively). Physicians' influenza vaccine recommendation was higher in the severe motor dysfunction group, and the difference was statistically significant (p = 0.029). Conclusion: Children with CP had lower immunization rates and incomplete immunization programs. Clinicians must ensure children with CP receive the same preventative health measures as healthy children, including vaccines.en_US
dc.identifier.doi10.1007/s00431-021-04219-4
dc.identifier.issn0340-6199
dc.identifier.issn1432-1076
dc.identifier.pmid34355277en_US
dc.identifier.scopus2-s2.0-85111859160en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1007/s00431-021-04219-4
dc.identifier.urihttps://hdl.handle.net/20.500.14034/158
dc.identifier.wosWOS:000681539900002en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.journalEuropean Journal Of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCerebral palsyen_US
dc.subjectImmunization statusen_US
dc.subjectRespiratory infectionsen_US
dc.subjectPneumococcusen_US
dc.subjectInfluenzaen_US
dc.subjectInfluenza Vaccinationen_US
dc.subjectChildrenen_US
dc.subjectCoverageen_US
dc.subjectClassificationen_US
dc.subjectTimelinessen_US
dc.subjectDefinitionen_US
dc.subjectRisken_US
dc.titleEvaluation of immunization status in patients with cerebral palsy: a multicenter CP-VACC studyen_US
dc.typeArticleen_US

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