Platelet-Lymphocyte ratio is a predictor for the development of no-reflow phenomenon in patients with ST-segment elevation myocardial infarction after thrombus aspiration

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dc.authorscopusid56157249300
dc.authorscopusid55993139900
dc.authorscopusid56054200300
dc.authorscopusid56943414500
dc.authorscopusid26635348200
dc.authorwosidEMREN, Zeynep YAPAN/AAV-8842-2021
dc.contributor.authorŞenöz, Oktay
dc.contributor.authorEmren, Sadık Volkan
dc.contributor.authorErsecgin, Ahmet
dc.contributor.authorYapan Emren, Zeynep
dc.contributor.authorGül, İlker
dc.date.accessioned2022-02-15T16:58:28Z
dc.date.available2022-02-15T16:58:28Z
dc.date.issued2021
dc.departmentBakırçay Üniversitesien_US
dc.description.abstractBackround We aimed to evaluate the utility of the preprocedural platelet-lymphocyte ratio (PLR) for predicting the no-reflow phenomenon after thrombus aspiration during percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI). Method We retrospectively analyzed postprocedural thrombolysis in myocardial infarction (TIMI) flow grades and myocardial blush grades (MBG) of 247 patients who underwent a PCI procedure with thrombus aspiration.We divided these patients into two groups according to whether they had no-reflow (TIMI < 3, MBG < 2) or not (TIMI 3, MBG >= 2). Results No-reflow developed in 43 (17%) patients.Preprocedural PLR was significantly higher in the no-reflow group (183.76 +/- 56.65 vs 118.32 +/- 50.42 p < 0.001).Independent predictors of no-reflow were as follows: higher preprocedural platelet-lymphocyte ratio (PLR) (OR = 1.018; 95% CI = 1.004, 1.033; p = 0.013),mean corpuscular volume (MCV) (OR = 1.118; 95% CI = 1.024, 1.220; p = 0.012) and SYNTAX Score-2 (OR = 1.073; 95% CI = 1.005, 1.146; p = 0.036). PLR of 144 had 79% sensitivity and 75% specificity for the prediction of no-reflow. Conclusion PLR is a reliable predictor for no-reflow in STEMI patients undergoing thrombus aspiration.en_US
dc.identifier.doi10.1002/jcla.23795
dc.identifier.issn0887-8013
dc.identifier.issn1098-2825
dc.identifier.issue6en_US
dc.identifier.pmid33945171en_US
dc.identifier.scopus2-s2.0-85105043437en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1002/jcla.23795
dc.identifier.urihttps://hdl.handle.net/20.500.14034/413
dc.identifier.volume35en_US
dc.identifier.wosWOS:000646681500001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.journalJournal Of Clinical Laboratory Analysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectmanual thrombus aspirationen_US
dc.subjectno reflowen_US
dc.subjectplatelet to lymphocyte ratioen_US
dc.subjectprimary percutaneous coronary interventionen_US
dc.subjectST&#8208en_US
dc.subjectsegment elevation myocardial infarctionen_US
dc.titlePlatelet-Lymphocyte ratio is a predictor for the development of no-reflow phenomenon in patients with ST-segment elevation myocardial infarction after thrombus aspirationen_US
dc.typeArticleen_US

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