Prevalence of musculoskeletal pain and its impact on quality of life and functional exercise capacity in patients with pulmonary arterial hypertension

Basit Öğe Kaydı
dc.authoridSinan, Umit Yasar/0000-0002-4837-7099
dc.authoridzeren, Melih/0000-0002-9749-315X
dc.authorwosidSinan, Umit Yasar/A-7003-2017
dc.authorwosidzeren, Melih/HNR-7817-2023
dc.contributor.authorZeren, Melih
dc.contributor.authorDemir, Rengin
dc.contributor.authorSinan, Ümit Yaşar
dc.contributor.authorMustafaoğlu, Rüstem
dc.contributor.authorYıldız, Abdurrahim
dc.contributor.authorKüçükoğlu, Mehmet Serdar
dc.date.accessioned2023-03-22T19:47:33Z
dc.date.available2023-03-22T19:47:33Z
dc.date.issued2022
dc.departmentBelirleneceken_US
dc.description.abstractBackground: In pulmonary arterial hypertension (PAH), pathophysiological consequences of the disease and the drugs used to treat PAH may adversely affect musculoskeletal system. Aim of the study was to evaluate musculoskeletal pain prevalence and its impact on quality of life (QoL) and exercise capacity in PAH patients. Methods: 61 PAH patients were evaluated with Nordic Musculoskeletal Questionnaire (NMQ) for musculoskeletal pain presence, EmPHasis-10 and Minnesota Living with Heart Failure Questionnaire (MLHFQ) for QoL, 6-min walk test (6MWT) for functional exercise capacity and International Physical Activity Questionnaire-Short Form (IPAQ-SF) for physical activity participation. Results: 77% of PAH patients reported musculoskeletal pain. Pain prevalence was highest at low back (38%), followed by knees (36%), shoulders (36%) and neck (33%). Hemodynamic indicators of PAH severity were associated with pain presence in various parts of the body. Patients receiving any PAH-specific drug were more likely to experience pain compared to the patients whose drug therapy has not yet been initiated (RR = 1.6-2.0). Pain presence in neck, shoulder, low back and knees significantly correlated to worse QoL scores in both EmPHasis-10 and MLHFQ (p < 0.05). Pain presence in knees had the strongest influence on QoL, and it was the only significant correlate of 6MWT (r =-0.424) and IPAQ-SF (r =-0.264) (p < 0.05). Conclusions: Musculoskeletal pain is a common complaint in PAH patients, which significantly impairs QoL and physical functioning. Treatment strategies should include a more comprehensive assessment for musculoskeletal pain complaints of these patients and address pain presence accordingly, which may help providing a better management for PAH.en_US
dc.identifier.doi10.1016/j.rmed.2022.106759
dc.identifier.issn0954-6111
dc.identifier.issn1532-3064
dc.identifier.pmid35134632en_US
dc.identifier.scopus2-s2.0-85124191474en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.rmed.2022.106759
dc.identifier.urihttps://hdl.handle.net/20.500.14034/767
dc.identifier.volume193en_US
dc.identifier.wosWOS:000759649200004en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B Saunders Co Ltden_US
dc.relation.journalRespiratory Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPulmonary arterial hypertensionen_US
dc.subjectMusculoskeletal systemen_US
dc.subjectPainen_US
dc.subjectQuality of lifeen_US
dc.subjectFunctional exercise capacityen_US
dc.subjectDrug therapyen_US
dc.subjectPhysical-Activity Questionnaireen_US
dc.subjectLow-Back-Painen_US
dc.subjectMuscle Strengthen_US
dc.subjectKnee Painen_US
dc.subjectDiseaseen_US
dc.subjectOsteoarthritisen_US
dc.subjectReliabilityen_US
dc.titlePrevalence of musculoskeletal pain and its impact on quality of life and functional exercise capacity in patients with pulmonary arterial hypertensionen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
m. zeren.pdf
Boyut:
425.05 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam metin / Full text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Fizyoterapi ve Rehabilitasyon Bölümü Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu