Sociodemographic and clinical risk factors associated with in-hospital tuberculosis mortality in Turkiye, 2008-2018

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dc.authoridPolat, Gulru/0000-0002-2211-1268
dc.authoridErbaycu, Ahmet Emin/0000-0001-6618-6774
dc.authoridOzdemir, Ozer/0000-0002-8884-0682
dc.contributor.authorGayaf, Mine
dc.contributor.authorAyik Turk, Merve
dc.contributor.authorOzdemir, Ozer
dc.contributor.authorPolat, Gulru
dc.contributor.authorKaraman, Onur
dc.contributor.authorGuldaval, Filiz
dc.contributor.authorAri, Gulsum
dc.date.accessioned2025-03-20T09:50:26Z
dc.date.available2025-03-20T09:50:26Z
dc.date.issued2024
dc.departmentİzmir Bakırçay Üniversitesi
dc.description.abstractIntroduction: Tuberculosis (TB) is an infectious disease that can be fatal if left untreated or poorly treated, and it is associated with many morbidities. Deaths may provide better understanding of the associated factors and help guide interventions to reduce mortality. In this study, it was aimed to reveal some of the features that predict hospital mortality in patients with TB and to present some alarming findings for clinicians. Materials and Methods: Patients who had been hospitalized with the diagnosis of TB between January 2008 and December 2018 were included and analyzed retrospectively. In -hospital mortality because of any TB disease after the initiation of treatment in patients admitted to the TB Ward and the primary cause of mortality were taken as endpoint. Results: A total of 1321 patients with a mean age of 50.1 years were examined. Total mortality was 39.4% (521 deaths) and 13.1% were in -hospital deaths (173 deaths). Of the deaths, 61.8% (n= 107) occurred during the first month after TB treatment were started. On univariate analysis, age over 48.5 years, Charlson comorbidity index, extension of radiological involvement, hypoalbuminemia and lymphopenia were most predictive variables with higher odds ratios (respectively, p< 0.001 for all). Conclusion: In -hospital tuberculosis disease mortality is related with older age, cavitary or extensive pulmonary involvement, low albumin levels, unemployment, cigarette smoking and especially those with concomitant malignancy and chronic pulmonary disease.
dc.identifier.doi10.5578/tt.202401864
dc.identifier.issn0494-1373
dc.identifier.issue1
dc.identifier.pmid38676595
dc.identifier.scopus2-s2.0-85189006761
dc.identifier.scopusqualityQ3
dc.identifier.trdizinid1229401
dc.identifier.urihttps://doi.org/10.5578/tt.202401864
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1229401
dc.identifier.urihttps://hdl.handle.net/20.500.14034/2184
dc.identifier.volume72
dc.identifier.wosWOS:001244827300007
dc.identifier.wosquality#YOK
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish Assoc Tuberculosis & Thorax
dc.relation.ispartofTuberkuloz ve Toraks-Tuberculosis and Thorax
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250319
dc.subjectTuberculosis
dc.subjectin-hospital mortality
dc.subjectpulmonary involvement
dc.subjectrisk factors
dc.subjectmorbidity
dc.titleSociodemographic and clinical risk factors associated with in-hospital tuberculosis mortality in Turkiye, 2008-2018
dc.typeArticle

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