Prognostic effects of neutrophil-lymphocyte rates in serum and pleural fluids in malignant pleural fluids

Basit Öğe Kaydı
dc.contributor.authorAyrancı, Aysu
dc.contributor.authorYavuz, Melike Yüksel
dc.contributor.authorAnar, Ceyda
dc.contributor.authorKaradeniz, Gülistan
dc.contributor.authorPolat, Gülru
dc.contributor.authorBüyükşirin, Melih
dc.contributor.authorGüldaval, Filiz
dc.date.accessioned2023-03-22T19:48:12Z
dc.date.available2023-03-22T19:48:12Z
dc.date.issued2021
dc.departmentBelirleneceken_US
dc.description.abstractObjective: Various studies have reported that the neutrophil-to-lymphocyte ratio in the serum (sNLR) may serve as a cost-effective and useful prognostic factor in patients with various cancer types. We investigated the clinical impact of NLR as a prognostic factor in malign pleural effusion (MPE) and sNLR on prognosis in MPE. Method: We retrospectively reviewed all of the patients who were diagnosed MPE. The relationship between sNLR and neutrophil-to-lymphocyte ratio in the malign pleural effusion (mNLR) value, age, Eastern Cooperative Oncology Group (ECOG), histopathologic type, serum albumin and lactate dehydrogenase (LDH) with survival were investigated. Results: A total of 222 patients with a mean age of 65.7±11.5 were included in the study. Patients with a mNLR value ?0.42 and a serum NLR value ?4.75 had a shorter survival (p: 0.000). Multivariate analysis, which showed that survival was significantly related mNLR value > 0.42 and/or sNLR value > 4.75 (Odds Ratio (OR): 2.66, %95 CI, 1,65-4,3 p: 0.001), serum LDH > 210 (OR = 1.8, %95 CI, 1,33-2,46 p: 0.001) and age > 65 (OR = 1.9, %95 CI, 1,41-2,55 p = 0.001). Conclusion: sNLR and mNLR may act as a simple, useful, and cost-effective prognostic factor in patients with MPE. Furthermore, these results may serve as the cornerstone of further research into the mNLR in the future. Although further studies are required to generalize our results, this information will benefit clinicians and patients in determining the most appropriate therapy for patients with MPE.en_US
dc.identifier.doi10.5222/IGH.2021.91300
dc.identifier.endpage8en_US
dc.identifier.issn1300-4115
dc.identifier.issue3en_US
dc.identifier.startpage1en_US
dc.identifier.trdizinid484321en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14034/1013
dc.identifier.urihttps://doi.org/10.5222/IGH.2021.91300
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/484321
dc.identifier.volume35en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.journalİzmir Göğüs Hastanesi Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titlePrognostic effects of neutrophil-lymphocyte rates in serum and pleural fluids in malignant pleural fluidsen_US
dc.title.alternativeMalign plevral sıvılarda plevral sıvı ve serum nötrofil-lenfosit oranının prognostik etkisi
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Prognostic effects of neutrophil-lymphocyte rates in serum and pleural fluids in malignant pleural fluids.pdf
Boyut:
1.08 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam metin / Full text
İndir

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu
Dahili Tıp Bilimleri Bölümü Koleksiyonu