Producing Fluorine- and Lubricant-Free Flexible Pathogen- and Blood-Repellent Surfaces Using Polysiloxane-Based Hierarchical Structures

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dc.authoridDidar, Tohid/0000-0002-8757-8002
dc.authoridLadouceur, Liane/0000-0002-7139-8162
dc.authoridKhan, Shadman/0000-0002-5088-3441
dc.contributor.authorLadouceur, Liane
dc.contributor.authorShakeri, Amid
dc.contributor.authorKhan, Shadman
dc.contributor.authorRincon, Alejandra Rey
dc.contributor.authorKasapgil, Esra
dc.contributor.authorWeitz, Jeffrey I.
dc.contributor.authorSoleymani, Leyla
dc.date.accessioned2023-03-22T19:47:34Z
dc.date.available2023-03-22T19:47:34Z
dc.date.issued2022
dc.departmentBelirleneceken_US
dc.description.abstractHigh-touch surfaces are known to be a major route for the spread of pathogens in healthcare and public settings. Antimicrobial coatings have, therefore, garnered significant attention to help mitigate the transmission of infectious diseases via the surface route. Among antimicrobial coatings, pathogen-repellent surfaces provide unique advantages in terms of safety in public settings such as instant repellency, affordability, biocompatibility, and long-term stability. While there have been many advances in the fabrication of biorepellent surfaces in the past two decades, this area of research continues to suffer challenges in scalability, cost, compatibility with high-touch applications, and performance for pathogen repellency. These features are critical for high-touch surfaces to be used in public settings. Additionally, the environmental impact of manufacturing repellent surfaces remains a challenge, mainly due to the use of fluorinated coatings. Here, we present a flexible hierarchical coating with straightforward and cost-effective manufacturing without the use of fluorine or a lubricant. Hierarchical surfaces were prepared through the growth of polysiloxane nanostructures using n-propyltrichlorosilane (n-PTCS) on activated polyolefin (PO), followed by heat shrinking to induce microscale wrinkles. The developed coatings demonstrated repellency, with contact angles over 153 degrees and sliding angles <1 degrees. In assays mimicking touch, these hierarchical surfaces demonstrated a 97.5% reduction in transmission of Escherichia coli (E.coli), demonstrating their potential as antimicrobial coatings to mitigate the spread of infectious diseases. Additionally, the developed surfaces displayed a 93% reduction in blood staining after incubation with human whole blood, confirming repellent properties that reduce bacterial deposition.en_US
dc.description.sponsorshipNSERC Discovery grant; Ontario Early Researcher Award (ERA) grant; McMaster start-up fundsen_US
dc.description.sponsorshipThis work was supported by the NSERC Discovery grant, Ontario Early Researcher Award (ERA) grant, and McMaster start-up funds to T.F.D. T.F.D and L.S are Tier II Canada Research Chairs.en_US
dc.identifier.doi10.1021/acsami.1c21672
dc.identifier.issn1944-8244
dc.identifier.issn1944-8252
dc.identifier.pmid35040309en_US
dc.identifier.scopus2-s2.0-85123878887en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1021/acsami.1c21672
dc.identifier.urihttps://hdl.handle.net/20.500.14034/770
dc.identifier.wosWOS:000745162500001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAmer Chemical Socen_US
dc.relation.journalAcs Applied Materials & Interfacesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectfluorine-free repellent surfacesen_US
dc.subjectlubricant-free repellent surfacesen_US
dc.subjectsuperhydrophobicityen_US
dc.subjecthierarchical surfacesen_US
dc.subjectpolysiloxane nanostructuresen_US
dc.subjectpathogen-repellent surfacesen_US
dc.subjectSuperhydrophobic Surfaceen_US
dc.subjectSilicone Nanofilamentsen_US
dc.subjectFabricationen_US
dc.subjectResistanten_US
dc.subjectCoatingsen_US
dc.subjectOilen_US
dc.subjectNanostructuresen_US
dc.subjectTransparenten_US
dc.subjectWettabilityen_US
dc.subjectAcidsen_US
dc.titleProducing Fluorine- and Lubricant-Free Flexible Pathogen- and Blood-Repellent Surfaces Using Polysiloxane-Based Hierarchical Structuresen_US
dc.typeArticleen_US

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