Demographics and clinical features of pediatric patients with allergic rhinitis: a single-center study from Western Turkey

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dc.contributor.authorBakir, Damla Baysal
dc.contributor.authorYagmur, Halime
dc.contributor.authorKabadayi, Gizem
dc.contributor.authorBoyacioglu, Ozge Kangalli
dc.contributor.authorAtay, Ozge
dc.contributor.authorAsilsoy, Suna
dc.contributor.authorUzuner, Nevin
dc.date.accessioned2025-03-20T09:50:45Z
dc.date.available2025-03-20T09:50:45Z
dc.date.issued2025
dc.departmentİzmir Bakırçay Üniversitesi
dc.description.abstractBackground Allergic rhinitis (AR) is a disease that has significant effects on the quality of life of people and exhibits different phenotypic features with different clinical findings. By analyzing the data of pediatric patients, we aimed to reveal the relationship between demographic and laboratory data and clinical features and to gain awareness about allergic rhinitis phenotypes in children. Methods Demographic data, clinical complaints, physical examination findings, and atopy biomarkers are retrospectively analyzed to assess the impact of aeroallergens on the disease phenotype. Results In a study of 301 AR patients (median age 11 years; 66.1% male), sneezing (79.1%) was the most common complaint, and pallor of the nasal mucosa was the primary examination finding (83.1%). Persistent symptoms were reported by 62.1%, and 60.5% were polysensitized. Notably, 42.5% had asthma, often associated with concurrent sensitization to mold or animal dander (p <= 0.05). Pollen was the most prevalent allergen (65.8%), with significant increases in sensitization to pollen (p < 0.001) and animal dander (p = 0.003) with age. Patients with pollen sensitization reported more sneezing (p = 0.026) and persistent symptoms (p <= 0.05). Nasal congestion was predominantly seen in house dust mite-sensitized patients (78.4% with concha hypertrophy, p < 0.001). Overall, it was found that 59.7% of monosensitized patients and 63.7% of polysensitized patients reported persistent complaints. Conclusion This study, conducted in Western Turkey with 301 allergic rhinitis patients, revealed a high prevalence of polysensitization, particularly to pollen and animal dander. Polysensitized patients were older, exhibited higher IgE levels, and more frequently reported sneezing and rhinorrhea. Furthermore, polysensitization was linked to more persistent and severe symptoms, emphasizing the need for personalized treatment strategies for these patients. Our findings highlight the importance of developing individualized and region-specific approaches to enhance the effectiveness of allergic rhinitis management.
dc.identifier.doi10.1186/s12887-025-05541-8
dc.identifier.issn1471-2431
dc.identifier.issue1
dc.identifier.pmid40050764
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1186/s12887-025-05541-8
dc.identifier.urihttps://hdl.handle.net/20.500.14034/2288
dc.identifier.volume25
dc.identifier.wosWOS:001439676600001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBMC
dc.relation.ispartofBmc Pediatrics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250319
dc.subjectAsthma
dc.subjectAllergen
dc.subjectChildren
dc.subjectPhenotype
dc.subjectSensitization
dc.titleDemographics and clinical features of pediatric patients with allergic rhinitis: a single-center study from Western Turkey
dc.typeArticle

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