The importance of GRACE risk score in the development of high-grade atrioventricular conduction blocks after non-st-segment elevation myocardial infarction

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dc.authorscopusid58679960100
dc.authorscopusid55754659100
dc.authorscopusid58823079900
dc.contributor.authorUyan U.
dc.contributor.authorAydin C.
dc.contributor.authorGül İ.
dc.date.accessioned2024-03-09T19:40:00Z
dc.date.available2024-03-09T19:40:00Z
dc.date.issued2023
dc.departmentİzmir Bakırçay Üniversitesien_US
dc.description.abstractOBJECTIVE: The development of high-grade atrioventricular block (HG-AVB) after acute coronary syndrome (ACS) increases morbidity and mortality rates. A significant portion of HG-AVBs resolve spontaneously after revascularization. We aimed to evaluate the power of the GRACE scoring system in predicting the development of HG-AVB and its importance in determining the need for cardiac pacemakers. PATIENTS AND METHODS: Patients who applied to our center between July 2020 and February 2023 were included in the study. 600 patients [340 (56.6%) male, mean age 65.4±13.6] without ST-segment elevation (NSTEMI) and who underwent revascularization were evaluated within the scope of the study. The heart rhythms of the patients were evaluated from the electrocardiograms (ECG) at admission. Patients with HG-AVB and other patients were divided into two groups. The heart rhythms of these patients were evaluated during their hospitalization. Then, HG-AVB patients were also divided into two groups (with and without PPM need). Demographic, laboratory, angiographic, and echocardiographic characteristics of these patients were evaluated. RESULTS: Morbidity and mortality were higher in the HG-AVB group. These patients had longer intensive care and hospital stays. The mean age, creatinine value, GRACE score (GS), total cholesterol (TC), and RCA lesion rates were higher in the HG-AVB group; hemoglobin level was found to be lower. As a result of regression analysis, RCA lesion, hemoglobin value, GRACE score, creatinine, and TC levels were predictors of HG-AVB development. In determining the need for PPM, these variables were found to be effective. ROC analysis was performed for GS, which predicted the development of HG-AVB, and the cut-off value was found to be 185.5. CONCLUSIONS: The development of HG-AVB after NSTEMI is an important health problem. By detecting these patients and those who may need PPM beforehand, various complications can be prevented, and the length of stay in the hospital can be shortened. Calculation of GS is an important parameter that can be used to predict the development and course of HG-AVB. © 2023 Verduci Editore s.r.l. All rights reserved.en_US
dc.identifier.doi10.26355/eurrev_202310_34151
dc.identifier.endpage9780en_US
dc.identifier.issn1128-3602
dc.identifier.issue20en_US
dc.identifier.pmid37916341en_US
dc.identifier.scopus2-s2.0-85175769984en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage9773en_US
dc.identifier.urihttps://doi.org/10.26355/eurrev_202310_34151
dc.identifier.urihttps://hdl.handle.net/20.500.14034/1620
dc.identifier.volume27en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Editore s.r.len_US
dc.relation.ispartofEuropean Review for Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGRACE risk score; High-grade atrioventricular conduction block; Non-ST segment elevation myocardial infarction; Permanent pacemakeren_US
dc.subjectcholesterol; creatinine; hemoglobin; creatinine; hemoglobin; age distribution; aged; angiography; Article; atrioventricular block; cholesterol blood level; controlled study; creatinine blood level; demographics; diagnostic test accuracy study; echocardiography; electrocardiography; female; GRACE risk score; heart muscle revascularization; hemoglobin blood level; high grade atrioventricular block; hospital admission; hospitalization; human; intensive care; length of stay; major clinical study; male; morbidity; mortality rate; non ST segment elevation myocardial infarction; prediction; receiver operating characteristic; regression analysis; right coronary artery; sensitivity and specificity; sinus node; atrioventricular block; middle aged; non ST segment elevation myocardial infarction; risk assessment; risk factor; Aged; Atrioventricular Block; Creatinine; Female; Hemoglobins; Humans; Male; Middle Aged; Non-ST Elevated Myocardial Infarction; Risk Assessment; Risk Factorsen_US
dc.titleThe importance of GRACE risk score in the development of high-grade atrioventricular conduction blocks after non-st-segment elevation myocardial infarctionen_US
dc.typeArticleen_US

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