Association of polycystic ovary syndrome with mammographic density in Turkish women: a population-based case-control study

Basit Öğe Kaydı
dc.authoridkebabci, eyup/0000-0001-8900-2325
dc.authoridOztekin, Deniz/0000-0002-4213-7254
dc.authoridAri, Sabahattin Anil/0000-0002-2526-6986
dc.authoridSenkaya, Ayse Rabia/0000-0003-1538-6965
dc.authorwosidkebabci, eyup/HLV-8646-2023
dc.authorwosidOztekin, Deniz/AAT-3898-2021
dc.authorwosidAri, Sabahattin Anil/AAY-5352-2021
dc.authorwosidŞenkaya, Ayşe Rabia/AFA-3669-2022
dc.authorwosidKARACA, İBRAHİM/K-6772-2019
dc.contributor.authorSenkaya, Ayse Rabia
dc.contributor.authorAri, Sabahattin Anil
dc.contributor.authorKaraca, Ibrahim
dc.contributor.authorKebapci, Eyup
dc.contributor.authorIsmailoglu, Eren
dc.contributor.authorOztekin, Deniz Can
dc.date.accessioned2024-03-09T18:48:44Z
dc.date.available2024-03-09T18:48:44Z
dc.date.issued2023
dc.departmentİzmir Bakırçay Üniversitesien_US
dc.description.abstractOBJECTIVE: The objective of this study was to investigate the breast densities and Breast Imaging-Reporting and Data System scores of patients with polycystic ovary syndrome and normoovulatory women and to determine whether these patients constitute a high-risk population for breast cancer.METHODS: This retrospective case-control study was conducted at our institution between January 2022 and December 2022, involving patients diagnosed with polycystic ovary syndrome. Menstrual periods, hyperandrogenemic findings, and ultrasound reports of the patients were retrieved from our hospital's database. Patients who met at least two of the Rotterdam criteria were included in the polycystic ovary syndrome group. A total of 70 premenopausal patients over the age of 40 years, diagnosed with polycystic ovary syndrome, and 70 normoovulatory women, matched for age and body mass index, were included in the study. The two groups were compared regarding age at menarche, menstrual pattern, gravida, parity, levels of follicle-stimulating hormone, luteinizing hormone, and estradiol, endometrial thickness, breast density category, and Breast Imaging-Reporting and Data System classifications.RESULTS: Patients in the polycystic ovary syndrome group had a higher age at menarche (12.7 vs. 12.3, p=0.006). There was no difference between the gonadotropin levels in both groups. However, the estradiol level was higher in the polycystic ovary syndrome group (p<0.001). There was no statistically significant difference between the two groups in terms of breast density and Breast Imaging-Reporting and Data System scores (p=0.319 and p=0.650, respectively).CONCLUSION: Although we can conclude that the risk of breast malignancy is not increased in patients with polycystic ovary syndrome, the impact of the complex hormonal status of polycystic ovary syndrome on breast cancer remains unclear in the literature.en_US
dc.identifier.doi10.1590/1806-9282.20230138
dc.identifier.issn0104-4230
dc.identifier.issn1806-9282
dc.identifier.issue10en_US
dc.identifier.pmid37729221en_US
dc.identifier.scopus2-s2.0-85171812300en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1590/1806-9282.20230138
dc.identifier.urihttps://hdl.handle.net/20.500.14034/1440
dc.identifier.volume69en_US
dc.identifier.wosWOS:001073582400001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAssoc Medica Brasileiraen_US
dc.relation.ispartofRevista Da Associacao Medica Brasileiraen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBreast; Breast Neoplasms; Mammography; Menarche; Polycystic Ovary Syndromeen_US
dc.titleAssociation of polycystic ovary syndrome with mammographic density in Turkish women: a population-based case-control studyen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
1440.pdf
Boyut:
430.78 KB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu