Comparison of polymerase chain reaction method with culture method in antenatal Group B Streptococcus screening

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dc.authoridkandemir, hulya/0000-0001-8218-1893
dc.authoridKOYUNCU OZYURT, OZLEM/0000-0003-1260-0671
dc.contributor.authorCopur, Dogukan
dc.contributor.authorOzyurt, Ozlem Koyuncu
dc.contributor.authorKandemir, Hulya
dc.contributor.authorOzhak, Betil
dc.contributor.authorOgunc, Dilara
dc.contributor.authorMendilcioglu, Inanc
dc.date.accessioned2025-03-20T09:50:26Z
dc.date.available2025-03-20T09:50:26Z
dc.date.issued2024
dc.departmentİzmir Bakırçay Üniversitesi
dc.description.abstractObjectives:The aim of this study was to investigate the prevalence of Group BStreptococcus (GBS) colonization in pregnancies between 35 and 37 weeks of gestation and to compare the effectiveness of polymerase chain reaction (PCR) method with gold standard technique of culture in antenatal GBS screening. Material and methods: Vaginal and rectal swabs of a total of 106 pregnant women between 35th and 37th weeks of gestation, who were admitted to our clinic between January 2022 and August 2022, were evaluated using culture and PCR method. The prevalence of GBS was estimated. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of the PCR method were analyzed. Results: The prevalence of GBS was 10.4% and 21.69% using the culture and PCR method, respectively. Compared to the culture, the sensitivity, specificity, PPV, NPV and accuracy of PCR were found to be 100%, 87%, 47%, 100%, and 88%, respectively. Conclusions:This study results suggest that the PCR method is a simple, effective and fast method with high sensitivity, specificity, PPV, and NPV in antenatal GBS screening.
dc.identifier.doi10.5603/gpl.99055
dc.identifier.endpage939
dc.identifier.issn0017-0011
dc.identifier.issn2543-6767
dc.identifier.issue12
dc.identifier.pmid39287206
dc.identifier.scopus2-s2.0-85214327733
dc.identifier.scopusqualityQ3
dc.identifier.startpage935
dc.identifier.urihttps://doi.org/10.5603/gpl.99055
dc.identifier.urihttps://hdl.handle.net/20.500.14034/2182
dc.identifier.volume95
dc.identifier.wosWOS:001398602500001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherVia Medica
dc.relation.ispartofGinekologia Polska
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250319
dc.subjectGroup B Streptococcus
dc.subjectantenatal screening
dc.subjectculture
dc.subjectpolymerase chain reaction
dc.titleComparison of polymerase chain reaction method with culture method in antenatal Group B Streptococcus screening
dc.typeArticle

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