Stability of potassium, calcium and phosphorus electrolytes in three different tubes in patients with essential thrombocytosis

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dc.authoridBasok, Banu Isbilen/0000-0002-1483-997X
dc.authoridZeytinli Aksit, Merve/0000-0003-0212-1167
dc.authoridAksit, Murat/0000-0003-2106-9130
dc.authorwosidBasok, Banu Isbilen/AEJ-9148-2022
dc.authorwosidAksit, Murat/HDO-7081-2022
dc.contributor.authorAksit, Murat
dc.contributor.authorZeytinli Aksit, Merve
dc.contributor.authorColak, Ayfer
dc.contributor.authorIsbilen Basok, Banu
dc.contributor.authorCeylan, Cengiz
dc.date.accessioned2024-03-09T18:48:30Z
dc.date.available2024-03-09T18:48:30Z
dc.date.issued2023
dc.departmentİzmir Bakırçay Üniversitesien_US
dc.description.abstractProper blood collection and timely analysis are vital steps for reliable results. This study aims to compare potassium(K), calcium(Ca), and phosphorus(P) concentrations in serum separator tube (SST), lithium heparin tube without gel (LiH), and lithium heparin tube with a barrier (Barricor)tubes in essential thrombocytosis(ET) patients. Additionally, we assessed short-term stability of these analytes at room temperature. K, Ca and P concentrations of blood taken from 40 ET patients into SST, LiH and Barricor tubes were measured at 0, 2, 4 and 8 h. We calculated the percentage difference and defined the maximum permissible difference (MPD) using the Biological Variation Database. Intertube comparisons were conducted using Passing-Bablok regression and Bland-Altman analysis. Comparing SST to LiH, the percentage difference values for all tests exceeded the MPD. When comparing Barricor to LiH, K and Ca tests were above MPD, except for P. At the 8th hour, LiH showed clinically significant changes in all three electrolytes. Barricor exhibited stability for K, Ca, and P for up to 8 h, with only Ca levels borderline higher than the MPD. Our study reveals clinically significant alterations in K, Ca, and P concentrations in SST compared to LiH tubes, and in K and Ca concentrations in Barricor compared to LiH tubes. While K, Ca and P concentrations were stable for up to 4 h at room temperature in all tube types tested, significant changes were observed in all electrolytes at 8 h in the LiH tube.en_US
dc.identifier.doi10.1080/00365513.2023.2289162
dc.identifier.endpage590en_US
dc.identifier.issn0036-5513
dc.identifier.issn1502-7686
dc.identifier.issue8en_US
dc.identifier.pmid38063345en_US
dc.identifier.scopus2-s2.0-85179946143en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage582en_US
dc.identifier.urihttps://doi.org/10.1080/00365513.2023.2289162
dc.identifier.urihttps://hdl.handle.net/20.500.14034/1346
dc.identifier.volume83en_US
dc.identifier.wosWOS:001116962200001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofScandinavian Journal of Clinical & Laboratory Investigationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectElectrolytes; Hypercalcemia; Hyperkalemia; Hyperphosphatemia; Thrombocytosisen_US
dc.titleStability of potassium, calcium and phosphorus electrolytes in three different tubes in patients with essential thrombocytosisen_US
dc.typeArticleen_US

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