Relationship Between C-Reactive Protein, Uric Acid and Fibrinogen Levels and Insulin Resistance in Different Body Mass Indexes: Descriptive Research

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dc.authorscopusid57194695019
dc.authorscopusid57407523500
dc.contributor.authorAksit M.
dc.contributor.authorZeytinli Aksit M.
dc.date.accessioned2024-03-09T19:40:08Z
dc.date.available2024-03-09T19:40:08Z
dc.date.issued2023
dc.departmentİzmir Bakırçay Üniversitesien_US
dc.description.abstractChronic inflammation in obesity is the main factor that increases insulin resistance by causing changes in insulin sensitivity. Our study aimed to investigate the relationship between insulin resistance and C-reactive protein (CRP), uric acid, and fibrinogen levels in different body mass indexes (BMI). Material and Methods: In our study, patients who applied to our hospital with the complaint of overweight in 2021-2022 were retrospectively analyzed, and 149 women aged 20 and over were included in the study. Glucose, uric acid, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglyceride (TG), CRP, insulin, fibrinogen results, which were measured simultaneously with the height and weight measurements of the patients, were obtained from the laboratory information system. Results: The patients included in the study were 25 normal weight, 56 overweight, 53 obese and 15 morbidly obese according to BMI. The uric acid and TG levels of the overweight group were found to be significantly higher than the normal group (respectively; p=0.012, p=0.031), the CRP level of the morbidly obese group was found to be significantly higher than the normal, overweight, and obese groups (respectively; p<0.001, p<0.001, p=0.006). A significant positive correlation was found between Homeostatic Model Assessment for Insulin Resistance and CRP and uric acid (respectively; r=0.219, p=0.009; r=0.353, p<0,001). Conclusion: We think that uric acid levels in the early stage of obesity and CRP levels in the advanced stage may be a guide for insulin resistance and obesity-related diseases. 2146-9032 / Copyright © 2023 by Türkiye Klinikleri. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).en_US
dc.identifier.doi10.5336/cardiosci.2022-94122
dc.identifier.endpage26en_US
dc.identifier.issn1306-7656
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85174935504en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage21en_US
dc.identifier.urihttps://doi.org/10.5336/cardiosci.2022-94122
dc.identifier.urihttps://hdl.handle.net/20.500.14034/1647
dc.identifier.volume35en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherOrtadogŸu Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S.en_US
dc.relation.ispartofTurkiye Klinikleri Cardiovascular Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectC-reaktive protein; Fibrinogen; insulin resistance; obesity; uric aciden_US
dc.subjectC reactive protein; cholesterol; fibrinogen; glucose; high density lipoprotein cholesterol; insulin; low density lipoprotein cholesterol; triacylglycerol; uric acid; adult; anthropometric parameters; Article; biochemical analysis; body height; body mass; body weight; cholesterol blood level; comparative study; controlled study; descriptive research; early diagnosis; female; homeostasis model assessment; human; immunoassay; insulin resistance; major clinical study; male; morbid obesity; obesity; retrospective studyen_US
dc.titleRelationship Between C-Reactive Protein, Uric Acid and Fibrinogen Levels and Insulin Resistance in Different Body Mass Indexes: Descriptive Researchen_US
dc.title.alternativeFarklı Beden Kitle Indekslerinde C-Reaktif Protein, Urik Asit ve Fibrinojen Duzeyleri ile Insulin Direnci Arasındaki Ilişki: Tanımlayıcı Araştırmaen_US
dc.typeArticleen_US

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