Prognostic Significance of the Strong Ion Gap in Patients in Medical and Surgical Intensive Care Units

dc.contributor.authorAltun, Halil Ibrahim
dc.contributor.authorAltun, Gozde
dc.contributor.authorAltas, Omer Faruk
dc.contributor.authorAran, Gulcin
dc.date.accessioned2024-03-09T18:48:56Z
dc.date.available2024-03-09T18:48:56Z
dc.date.issued2023
dc.departmentİzmir Bakırçay Üniversitesien_US
dc.description.abstractBackgroundThis study aimed to analyze acid-base imbalance by assessing the arterial blood gas (ABG) samples of the medical and surgical intensive care unit (ICU) patients by the Stewart approach and demonstrate the advantages of this method in delineating the acid-base status in cases where Henderson-Hasselbalch, anion gap, and base excess cannot optimally depict the imbalance and create recognition in the clinicians in this regard.MethodologyAdult (i.e., age > 18 years) patients admitted to the ICU of our institution during a one-year study period were included in this study. The patients were divided into two groups based on the indication of admission to the ICU as medical or surgical. The ABG, sodium, potassium, calcium, magnesium, phosphate, chloride, albumin, lactate, hemoglobin, hematocrit, leukocyte, blood urea nitrogen, and creatinine values determined during the first 24-hour period were used for calculating the Acute Physiologic Assessment and Chronic Health Evaluation (APACHE II), strong ion difference apparent (SIDa), and SID effective (SIDe) scores, which were subsequently compared between the groups.ResultsOverall, 220 (110 medical and 110 surgical) patients were included. The mean patient age was 63.56 +/- 18.08 years. The mean APACHE II scores were 21.99 and 19.63 in the medical and surgical groups, respectively. Overall, 110 patients died, while 110 were referred to the regular patient floor. The mean APACHE II score of the patients who died was 28.3, and the latter group had a mean APACHE II score of 13.57. There was a significant difference between the surgical and medical patient groups regarding mean values of APACHE II, SIDa, and SIDe scores. Also, the differences were significant between the patients who died and were discharged. There was a significant difference between the patients who died and were discharged regarding the strong ion gap (SIG); however, the medical and surgical patient groups were not different concerning the SIG values.ConclusionsWe conclude that SIDa, SIDe, and SIG can be used in medical and surgical ICU patients to predict prognosis.en_US
dc.identifier.doi10.7759/cureus.47964
dc.identifier.issn2168-8184
dc.identifier.issue10en_US
dc.identifier.pmid38034207en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.7759/cureus.47964
dc.identifier.urihttps://hdl.handle.net/20.500.14034/1517
dc.identifier.volume15en_US
dc.identifier.wosWOS:001147250200007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringernatureen_US
dc.relation.ispartofCureus Journal of Medical Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMortality; Apache 2 Score; Acid -Base Imbalance; Stewart Approach; Intensive Care Unit Admissionen_US
dc.titlePrognostic Significance of the Strong Ion Gap in Patients in Medical and Surgical Intensive Care Unitsen_US
dc.typeArticleen_US

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