Six-minute stepper test for evaluating functional exercise capacity in patients with sarcoidosis

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dc.authoridzeren, Melih/0000-0002-9749-315X
dc.authoridDemir, Rengin/0000-0002-2901-2967
dc.authorwosidzeren, Melih/HNR-7817-2023
dc.contributor.authorZeren, Melih
dc.contributor.authorDemir, Rengin
dc.contributor.authorYildiz, Esma
dc.contributor.authorYigit, Zerrin
dc.contributor.authorAtmaca, Sema Nur
dc.contributor.authorAtahan, Ersan
dc.date.accessioned2023-03-22T19:47:35Z
dc.date.available2023-03-22T19:47:35Z
dc.date.issued2023
dc.departmentBelirleneceken_US
dc.description.abstractBackground: Researchers and clinicians may benefit from alternative tests that do not require large physical spaces or corridors for simply evaluating functional exercise capacity in the clinical practice. Objective: Aim of this study was to investigate whether six-minute stepper test (6MST) is a valid tool for measuring functional exercise capacity in patients with sarcoidosis. Methods: Thirty-six patients with sarcoidosis and 18 healthy controls were evaluated with 6MST and sixminute walk test (6MWT). Patients performed 6MST twice. Cardiovascular and symptom responses to tests including heart rate, blood pressure, SpO(2), levels of dyspnea and fatigue were recorded. Results: Receiver operating characteristic (ROC) curve analysis revealed an area under the ROC curve of 0.74 for 6MST in identifying the patients and controls, indicating acceptable discriminative ability. Patients performed significantly worse in 6MST compared to controls (277 +/- 54 vs 349 +/- 87 steps; p <0.001). 6MST was able to explain 66% of variance in 6MWT (p<0.001), and there was a strong relationship between 6MWT and 6MST (r = 0.812). SpO(2) responses to tests were similar, however, 6MST generated more severe heart rate, dyspnea and fatigue responses. Intraclass correlation coefficient calculated for initial and retest scores of 6MST was 0.990, indicating excellent test-retest reliability. However, there was a systematical improvement (similar to 4%) in retest 6MST scores. Conclusions: 6MST is a valid and reliable alternative test for measuring functional exercise capacity in sarcoidosis. 6MST may also help better testing the upper limits of cardiac system and physical endurance as it is more physically demanding than 6MWT. (C) 2022 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.hrtlng.2022.12.006
dc.identifier.endpage157en_US
dc.identifier.issn0147-9563
dc.identifier.issn1527-3288
dc.identifier.pmid36516608en_US
dc.identifier.scopus2-s2.0-85143965775en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage152en_US
dc.identifier.urihttps://doi.org/10.1016/j.hrtlng.2022.12.006
dc.identifier.urihttps://hdl.handle.net/20.500.14034/778
dc.identifier.volume58en_US
dc.identifier.wosWOS:000901839400003en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMosby-Elsevieren_US
dc.relation.journalHeart & Lungen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSarcoidosisen_US
dc.subjectExercise capacityen_US
dc.subjectFunctional capacityen_US
dc.subjectExercise testen_US
dc.subjectValidityen_US
dc.subjectWalk Testen_US
dc.subjectMuscle Strengthen_US
dc.subjectStatementen_US
dc.subjectAssociationen_US
dc.subjectIntoleranceen_US
dc.titleSix-minute stepper test for evaluating functional exercise capacity in patients with sarcoidosisen_US
dc.typeArticleen_US

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