Do the Amount of Fluid, Histopathology, Radiology and Pleurodesis Status Affect the Survival in Malignant Pleural Effusions?

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dc.contributor.authorBüyükşirin, Melih
dc.contributor.authorTatar, Dursun
dc.contributor.authorKaradeniz, Gülistan
dc.contributor.authorPolat, Gülru
dc.contributor.authorAksel, Nimet
dc.contributor.authorGüldaval, Filiz
dc.contributor.authorÜçsular, Fatma Demirci
dc.date.accessioned2023-03-22T19:48:17Z
dc.date.available2023-03-22T19:48:17Z
dc.date.issued2021
dc.departmentBelirleneceken_US
dc.description.abstractINTRODUCTION: The primary objective of this study was to identify the most common pleural malignancies leading to malign pleural effusion (MPE). The secondary objective was to evaluate the relationship between the amount of fluid and radiological findings, etiologies, treatment methods and survival. METHODS: We retrospectively included cases of MPE with a tissue diagnosis. RESULTS: The most common causes of MPE were lung cancer (73%), breast cancer (8.3%) and mesothelioma (7%). In patients who were offered chemical pleurodesis, pleurodesis was successful in nearly 31.1%. No relation wasfound between the amount of pleural fluid and cell type,survival, pulmonary, extrapulmonary malignancy and mesothelioma, Patients live longer if pleurodesis was successful (p = 0.005). Median survival of patients with MPE due to pulmonary, extrapulmonary and mesothelioma, ORCID: 0000-0002-8939-336X respectively were 77 ± 12.8, 150 ± 48.4 and 365 ± 0 days. The survival of the patients with mesothelioma was significantly longer than others (P: 0.000). DISCUSSION AND CONCLUSION: The main cause of MPE was lung cancer, followed by breast cancer, unknown primary and mesothelioma. Chemical pleurodesis was a viable palliative measure for MPE. Successful pleurodesis had a significant contribution to the survival.en_US
dc.identifier.doi10.5505/KTD.2021.44341
dc.identifier.endpage44en_US
dc.identifier.issn2147-0758
dc.identifier.issue2en_US
dc.identifier.startpage39en_US
dc.identifier.trdizinid516927en_US
dc.identifier.urihttps://doi.org/10.5505/KTD.2021.44341
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/516927
dc.identifier.urihttps://hdl.handle.net/20.500.14034/1046
dc.identifier.volume10en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.journalKocaeli Tıp Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleDo the Amount of Fluid, Histopathology, Radiology and Pleurodesis Status Affect the Survival in Malignant Pleural Effusions?en_US
dc.typeArticleen_US

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