Üçvet, AhmetYazgan, SerkanSamancılar, ÖzgürGürsoy, SonerErbaycu, Ahmet EminKömürcüoğlu, Berna2023-03-222023-03-2220211731-55301897-4252https://doi.org/10.5114/kitp.2021.112188https://hdl.handle.net/20.500.14034/743Introduction: We reviewed our surgical preferences and the prognosis for recurrent and second primary tumors in patients who underwent surgical treatment for non-small cell lung carcinoma (NSCLC). Aim: We report our experience with patients undergoing iterative pulmonary resection for lung cancer. Material and methods: Among patients who underwent anatomical resection for primary NSCLC, those who underwent a second surgical resection between 2010 and 2020 due to recurrent or second primary tumor were included in the study. Operative mortality, survival, and prognostic factors were investigated. Results: In total, 77 cases were included: 31 (40.3%) underwent the second resection for the recurrent disease and 46 (59.7%) underwent the second resection for the second primary tumor. Postoperative mortality occurred in 8 (10.4%) patients. All patients with postoperative mortality were in the group that underwent thoracotomy in both surgical procedures. The 5-year survival rate was 46.5%. The 5-year survival of those operated on for recurrent or second primary tumor was 32.8% and 51.1%, respectively (p = 0.81). The 5-year survival rate was 68.8% in patients under the age of 60 years, while it was 27.5% in patients aged 60 years and above (p = 0.004). The 5-year survival was 21.8% in patients with an interval of 36 months or less between two operations and 72.2% in those with a longer interval (p = 0.028). Conclusions: Our study shows that survival results similar to or better than primary NSCLC surgery can be obtained with lower mortality if more limited resections are performed via video-assisted thoracic surgery, especially in young patients. In addition, the prognosis is better in patients with an interval of more than 36 months between two operations.eninfo:eu-repo/semantics/openAccesslung cancermetachronoussynchronousrecurrencesurgeryCompletion PneumonectomyFollow-UpMortalityRecurrentSurvivalArticle10.5114/kitp.2021.112188184221226N/AWOS:0007427390000052-s2.0-8512336045635079263Q3