Keles, Ercan2024-03-092024-03-0920230268-35551758-1125https://doi.org/10.1177/02683555231190266https://hdl.handle.net/20.500.14034/1412Objectives In this study, we present the complication data of patients we treated for chronic venous insufficiency (CVI) with cyanoacrylate adhesive closure (CAC) therapy for 2 years. Methods Complications of 382 CAC procedures performed by the same surgeon were reviewed retrospectively. Results Independent of patients, depending on the payment system of the state; two hundred twenty-three (58.4%) of 382 procedures were performed using the Venex system, and the Variclose system was used in 159 (41.6%) patients. A phlebitis-like reaction occurred in 46 (12%) patients, induration in 18 (4.7%) patients, hyperpigmentation in five (1.3%) patients, abscesses in four (1%) patients, cellulitis in three (0.8%) patients, and granuloma in one (0.3%) patient. In addition, as serious complications, deep vein thrombosis (DVT) developed in three patients and pulmonary embolism in one of these patients. Interestingly, temporary blindness was also observed in one patient. Conclusions Although CAC therapy is a reliable method, its complications should not be ignored. Its use by experienced surgeons reduces the risk of complications.eninfo:eu-repo/semantics/closedAccessGlue; Cyanoacrylate; Venous Insufficiency; Cyanoacrylate Adhesive ClosureArticle10.1177/02683555231190266388550555N/AWOS:0010333521000012-s2.0-8516555860437471321Q3