Tutkun, Gılman TuğçeAltuntaş, MuratTürköz, İsmailArslan, NurtenKaş, Fadime Özge AygünGencer, EmineGemici, Ümit2023-03-222023-03-2220222687-4717https://hdl.handle.net/20.500.14034/1017https://doi.org/10.52827/hititmedj.1125430https://search.trdizin.gov.tr/yayin/detay/1137511Objective: We aimed to compare RT-PCR positive and RT-PCR negative patients with radiologically confirmed COVID-19 pneumonia admitted to the intensive care unit in terms of outcome and laboratory results in the inflammation process. Material and method: Patients who were admitted to the intensive care unit due to respiratory failure and had typical COVID-19 pneumonia findings on thorax tomograp- hy were included in the study. Patients were grouped as RT-PCR negative and RT-PCR positive. Groups were compared for descriptive and laboratory characteristics, treat- ments, length of stay and outcome. Results: Lactate, D-dimer levels, and leukocyte, neutrophil counts of the RT-PCR positive group were lower than the other group (p<0.05). Ferritin and CRP values were higher in the RT-PCR positive group (p<0.01). The duration between symptom onset and admission to intensive care unit was longer in the PCR-positive group(p=0.016). PaO2/FiO2 ratio was 193.58±60.26 in RT-PCR negative group, and 111.16±58.51 in RT-PCR positive group (p=0.01). There was no statistically significant difference between the groups in terms of length of stay, respiratory therapies or outcome (p>0.05). Conclusion: We may say that RT-PCR negative and RT-PCR positive patients were in different inflammation period in admission. We concluded that there was no differen- ce between groups in terms of outcome.eninfo:eu-repo/semantics/openAccessCOVID-19Intensive care unitPneumonia Reverse transcriptase COVID-19PnömoniRevers transkriptazYoğun bakımOther10.52827/hititmedj.11254304384881137511