KÖLE, EmreVATANSEVER, NefizeÖZDAŞ, Emel DOĞANÖZDAŞ, ErolTUNALI, ÇağdaşERDOĞAN, ÖzgürAKDEMİR, Celal2024-03-092024-03-0920231305-51512148-6190https://search.trdizin.gov.tr/yayin/detay/1179329https://hdl.handle.net/20.500.14034/1758Introduction: This study aimed to investigate the need to re-evaluate paraffin block pathology preparations of endometrial biopsy samples taken from patients diagnosed with atypical endometrial hyperplasia (AEH) at different institutions by expert gynaecologic pathologists before surgery at a tertiary hospital. Materials and Methods: This study included 116 patients diagnosed with AEH based on endometrial biopsy samples taken at different institutions between January 2017 and January 2021 and operated on at our clinic. The paraffin blocks of all patient samples included in the study were re-evaluated at the Pathology Department of our hospital (block consultation). Patients were divided into two groups as follows: those diagnosed with AEH based on endometrial biopsy at an external centre (all patients) and those diagnosed with AEH based on paraffin block examination. The post-operative pathology results of the two groups were compared. Results: Block consultation indicated AEH in 77 (66.4%) of the patients with AEH diagnosed at an external centre. Post-operative pathology results revealed that 15 (12.9%) patients had benign, 42 (36.2%) had AEH and 59 (50.9%) had malignant. On comparing the post-operative pathology results of the two groups, no significant difference was observed (p = 0.252). There was no significant difference between the two groups in terms of the grade and stage of the malignancy detected on post-operative pathological evaluation (p = 0.603 and p = 0.552, respectively). Conclusion: Although re-examination of the paraffin blocks of patients diagnosed with AEH based on endometrial biopsy samples taken at di fferent institutions by gynaecologic pathologists (block consultation) led to different results, no significant difference was noted on comparing the post-operative pathology results. To ensure that workload does not increase and to save time, patients diagnosed with AEH based on endometrial biopsy can be operated on without re-examining the paraffin blocks to confirm the diagnosis.eninfo:eu-repo/semantics/openAccessArticle2721311371179329