The Predictive Value of the Systemic Immune-Inflammation Index for the Progression of Lower Urinary Tract Symptoms in Men

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dc.authorscopusid52263906800
dc.authorscopusid55318881100
dc.authorscopusid57218293731
dc.authorscopusid13204221100
dc.authorscopusid57672963600
dc.contributor.authorHorsanali M.O.
dc.contributor.authorDil E.
dc.contributor.authorCaglayan A.
dc.contributor.authorEkren F.
dc.contributor.authorOzsagir Y.O.
dc.date.accessioned2024-03-09T19:40:01Z
dc.date.available2024-03-09T19:40:01Z
dc.date.issued2023
dc.departmentİzmir Bakırçay Üniversitesien_US
dc.description.abstractIntroduction: This retrospective cross-sectional observational study aimed to investigate the predictive value of the systemic immune-inflammation index (SII) for the progression of lower urinary tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH). Material and method: A total of 280 patients diagnosed with LUTS were analyzed, and their demographic characteristics, laboratory results, urological parameters, and SII levels were recorded retrospectively. Results: Clinical progression of LUTS was observed in 43.2% of the patients, with 23.9% undergoing surgery and 21.4% progressing to acute urinary retention. The study found that elevated SII levels were significantly correlated with disease progression and worse outcomes. Multivariate analysis revealed that peak urinary flow rate, erectile function scores, and platelet levels were risk factors for predicting clinical progression in LUTS/BPH patients. Conclusion: The findings suggest that systemic inflammation and immune dysregulation play a role in BPH pathogenesis and the development of LUTS. Incorporating SII assessment into routine clinical practice could aid in risk stratification, treatment decision-making, and monitoring of disease progression in LUTS/BPH patients. This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License.en_US
dc.identifier.doi10.31557/APJCP.2023.24.11.3845
dc.identifier.endpage3850en_US
dc.identifier.issn1513-7368
dc.identifier.issue11en_US
dc.identifier.pmid38019242en_US
dc.identifier.scopus2-s2.0-85178495146en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage3845en_US
dc.identifier.urihttps://doi.org/10.31557/APJCP.2023.24.11.3845
dc.identifier.urihttps://hdl.handle.net/20.500.14034/1624
dc.identifier.volume24en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAsian Pacific Organization for Cancer Preventionen_US
dc.relation.ispartofAsian Pacific Journal of Cancer Preventionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBenign prostatic hyperplasia; Lower urinary tract symptoms; Systemic immune-inflammation indexen_US
dc.subjectcomplication; cross-sectional study; disease exacerbation; human; inflammation; lower urinary tract symptom; male; prostate hypertrophy; retrospective study; Cross-Sectional Studies; Disease Progression; Humans; Inflammation; Lower Urinary Tract Symptoms; Male; Prostatic Hyperplasia; Retrospective Studiesen_US
dc.titleThe Predictive Value of the Systemic Immune-Inflammation Index for the Progression of Lower Urinary Tract Symptoms in Menen_US
dc.typeArticleen_US

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