The Effect of Childhood Obesity on Intraocular Pressure, Corneal Biomechanics, Retinal Nerve Fiber Layer, and Central Macular Thickness

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dc.contributor.authorAydin Eroglu, Sayime
dc.contributor.authorAkyuz Unsal, Ayse Ipek
dc.contributor.authorVerdi, Furkan
dc.contributor.authorKurt Omurlu, Imran
dc.contributor.authorUnuvar, Tolga
dc.contributor.authorAnik, Ahmet
dc.date.accessioned2025-03-20T09:44:57Z
dc.date.available2025-03-20T09:44:57Z
dc.date.issued2024
dc.departmentİzmir Bakırçay Üniversitesi
dc.description.abstractPrécis: Elevated corneal hysteresis (CH) and resistance factor (CRF) in obese and overweight children imply weight's effect on corneal biomechanics. Increased Goldmann-correlated intraocular pressure (IOPg) in obese children indicates glaucoma risk, emphasizing screening for IOP and retinal changes. Purpose: To evaluate the effect of obesity on corneal biomechanics, retinal nerve fiber layer (RNFL), and central macular thickness (CMT) in children. Patients and Methods: In this prospective, cross-sectional, comparative study, 146 eyes of normal-weight, over-weight, and obese children aged between 6 to 17 years were evaluated. The IOPg, corneal compensated IOP (IOPcc), CH, CRF, and the average retinal nerve fiber layer (RNFL), average cup-to-disk ratio (c/d), and central macular thickness (CMT) were measured by Ocular Response Analyser and Spectral-Domain Optical Coherence Tomography (SD-OCT), respectively. Results: There was no statistically significant difference regarding age, gender, IOPcc, average RNFL thickness, c/d ratio, and CMT among the groups (P≥0.05). The IOPg was significantly higher in obese children compared with normal-weight children, while CH and CRF values were significantly higher in both obese and over-weight children compared with healthy ones (P<0.05). There was a positive correlation between BMI percentile and IOPg, CH, and CRF values. Conclusion: In our study, higher IOPg, corneal hysteresis, and corneal resistance factor values suggest that obese children could be potential candidates for glaucoma. Therefore, it would be appropriate to screen them for IOP and retinal alterations. Further investigations with larger sample size and longer follow-up are needed to understand the risk of glaucoma in obese children. © 2024 Lippincott Williams and Wilkins. All rights reserved.
dc.identifier.doi10.1097/IJG.0000000000002372
dc.identifier.endpage421
dc.identifier.issn1057-0829
dc.identifier.issue6
dc.identifier.pmid38506830
dc.identifier.scopus2-s2.0-85195046574
dc.identifier.scopusqualityQ2
dc.identifier.startpage417
dc.identifier.urihttps://doi.org/10.1097/IJG.0000000000002372
dc.identifier.urihttps://hdl.handle.net/20.500.14034/2088
dc.identifier.volume33
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams and Wilkins
dc.relation.ispartofJournal of Glaucoma
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20250319
dc.subjectchildren
dc.subjectcorneal biomechanics
dc.subjectintraocular pressure
dc.subjectobesity
dc.subjectoptical coherence tomography (OCT)
dc.titleThe Effect of Childhood Obesity on Intraocular Pressure, Corneal Biomechanics, Retinal Nerve Fiber Layer, and Central Macular Thickness
dc.typeArticle

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