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    Six-minute stepper test for evaluating functional exercise capacity in patients with sarcoidosis
    (Mosby-Elsevier, 2023) Zeren, Melih; Demir, Rengin; Yildiz, Esma; Yigit, Zerrin; Atmaca, Sema Nur; Atahan, Ersan
    Background: Researchers and clinicians may benefit from alternative tests that do not require large physical spaces or corridors for simply evaluating functional exercise capacity in the clinical practice. Objective: Aim of this study was to investigate whether six-minute stepper test (6MST) is a valid tool for measuring functional exercise capacity in patients with sarcoidosis. Methods: Thirty-six patients with sarcoidosis and 18 healthy controls were evaluated with 6MST and sixminute walk test (6MWT). Patients performed 6MST twice. Cardiovascular and symptom responses to tests including heart rate, blood pressure, SpO(2), levels of dyspnea and fatigue were recorded. Results: Receiver operating characteristic (ROC) curve analysis revealed an area under the ROC curve of 0.74 for 6MST in identifying the patients and controls, indicating acceptable discriminative ability. Patients performed significantly worse in 6MST compared to controls (277 +/- 54 vs 349 +/- 87 steps; p <0.001). 6MST was able to explain 66% of variance in 6MWT (p<0.001), and there was a strong relationship between 6MWT and 6MST (r = 0.812). SpO(2) responses to tests were similar, however, 6MST generated more severe heart rate, dyspnea and fatigue responses. Intraclass correlation coefficient calculated for initial and retest scores of 6MST was 0.990, indicating excellent test-retest reliability. However, there was a systematical improvement (similar to 4%) in retest 6MST scores. Conclusions: 6MST is a valid and reliable alternative test for measuring functional exercise capacity in sarcoidosis. 6MST may also help better testing the upper limits of cardiac system and physical endurance as it is more physically demanding than 6MWT. (C) 2022 Elsevier Inc. All rights reserved.
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    The Effect of Computerized Wobble Board and Core Stabilization Exercises on Balance Performance and Exercise Capacity in Patients With Heart Failure: A Randomized Controlled Trial
    (W B Saunders Co-Elsevier Inc, 2024) Durdu, Habibe; Demir, Rengin; Zeren, Melih; Aydin, Ertan; Gunaydin, Zeki Yuksel; Yigit, Zerrin
    Objective: To investigate the effects of computerized wobble board exercise training (CWBET) and core stabilization exercise training (CSET) on balance performance, and exercise capacity in patients with heart failure (HF). Desing: Single-blind randomized controlled prospective study. Setting: Cardiology department of a local university hospital. Participants: Fifty-one patients with HF with reduced ejection fraction, whose clinical status and medication had been stable for the previous 3 months, were included (N=51). Nine patients could not complete the follow-up period due to personal reasons. No patient experienced any adverse events during exercise training. Interventions: Patients were randomized to CWBET, CSET, and control group. CWBET and CSET groups participated in their own exercise programs, 3 days a week for 8 weeks. The control group received no exercise program. Main Outcome Measures: All patients were evaluated at baseline and after 8 weeks. Postural stability, static and functional balance, and exercise capacity were evaluated with the Sensamove Balance Test Pro with Miniboard, the one-leg stance test (OLS), the Berg Balance Scale (BBS), and the six-minute walk distance (6MWD), respectively. Core stabilization and health-related quality of life (HRQOL) were assessed with OCTOcore app, and Minnesota Living with Heart Failure Questionnaire, respectively. Results: A mixed model repeated-measures ANOVA revealed significant group x time interaction effect for static postural stability performance (P<.001, eta(2)(p)=0.472), vertical (P<.001, eta(2)(p)=0.513), horizontal performance (P<.001, eta(2)(p)=0.467), OLS (P<.001, eta(2)(p)=0.474), BBS (P<.001, eta(2)(p)=0.440) scores, 6MWD (P<.001, eta(2)(p)=0.706), and HRQOL. Post hoc analysis revealed CWBET and CSET groups had similar improvements balance performance, exercise capacity, and HRQOL and both groups significantly improved compared with control group (P<.001). Core stabilization was significantly improved only in CSET group after 8 weeks. Conclusion: CWBET and CSET programs were equally effective and safe for improving balance performance and exercise capacity in patients with HF. (c) 2024 by the American Congress of Rehabilitation Medicine