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  • Küçük Resim
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    Clinical characteristics and transmission routes of COVID-19 in the early period of the pandemic in a non-covid ward of chest diseases hospital
    (2021) Karadeniz, Gülistan; Gayaf, Mine; Güldaval, Filiz; Ayrancı, Aysu; Batum, Özgür; Polat, Gülru; Tatar, Dursun
    Objective: In the early stages of the outbreak, Covid patients were followed-up in isolated Covid Wards, and the examinations of other pulmonary diseases continued in Non-Covid wards. Differential diagnosis between COVID-19 and infections caused by other pathogens is not adequately recognized. For this reason, it is even more difficult to identify patients who are infected with SARS-CoV2 or other pathogens. In the present study, the clinical characteristics and transmission routes of the Covid-19 cases in Non-Covid Wards within approximately 2 months’ time after the onset of the pandemic were analyzed speculatively. Method: In the early periods of the pandemic, quarantine wards were created for Covid patients in Chest Diseases Hospital, but there were also changes in Non-Covid patients and new Non-Covid hospitalizations. The clinical characteristics and transmission routes of the Covid cases in Non-Covid Ward were examined retrospectively and observationally between 10.03.2020 and 30.04.2020. Results: During this period, a total of 35 Covid cases were detected as a patient, companion and healthcare employees. The median age of the patients was 50 years (min-max 25-85). There were 17 patients (48.6%) who were not severe, and 18 severe patients (51.4%), and 10 (28.6%) patients died. A total of 25 (71,4%) of infected cases were verified with the SARS-CoV-2 Nucleic Acid Test, and 10 (28,6%) were diagnosed clinically and radiologically as possible COVID-19 cases. Being 65 years old or over, having comorbid diseases, especially COPD, the presence of dyspnea as a symptom and involvement on chest radiography were found to be significantly associated with survival (p0.027, 0.009, 0.038, 0.000 and 0.033, respectively). Lymphopenia, increase in neutrophil count, CRP and NLR value were found to be statistically related to survival (p 0.005, 0.001, 0.014 and 0.000, respectively). We found 4 super spreaders, one of whom was a companion, and 3 patients. Conclusion: Potential “super spreaders” can be the source of infection before the quarantine conditions are applied and comprehensive protection is implemented. For this reason, quarantine, use of personal protective equipment, application of social distancing, and the implementation of comprehensive preventive measures, such as disinfection, are crucial in controlling nosocomial infection.
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    Do the Amount of Fluid, Histopathology, Radiology and Pleurodesis Status Affect the Survival in Malignant Pleural Effusions?
    (2021) Büyükşirin, Melih; Tatar, Dursun; Karadeniz, Gülistan; Polat, Gülru; Aksel, Nimet; Güldaval, Filiz; Üçsular, Fatma Demirci
    INTRODUCTION: The primary objective of this study was to identify the most common pleural malignancies leading to malign pleural effusion (MPE). The secondary objective was to evaluate the relationship between the amount of fluid and radiological findings, etiologies, treatment methods and survival. METHODS: We retrospectively included cases of MPE with a tissue diagnosis. RESULTS: The most common causes of MPE were lung cancer (73%), breast cancer (8.3%) and mesothelioma (7%). In patients who were offered chemical pleurodesis, pleurodesis was successful in nearly 31.1%. No relation wasfound between the amount of pleural fluid and cell type,survival, pulmonary, extrapulmonary malignancy and mesothelioma, Patients live longer if pleurodesis was successful (p = 0.005). Median survival of patients with MPE due to pulmonary, extrapulmonary and mesothelioma, ORCID: 0000-0002-8939-336X respectively were 77 ± 12.8, 150 ± 48.4 and 365 ± 0 days. The survival of the patients with mesothelioma was significantly longer than others (P: 0.000). DISCUSSION AND CONCLUSION: The main cause of MPE was lung cancer, followed by breast cancer, unknown primary and mesothelioma. Chemical pleurodesis was a viable palliative measure for MPE. Successful pleurodesis had a significant contribution to the survival.
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    Göğüs hastalıkları onkolojik acillerin değerlendirilmesi
    (2020) Tatar, Dursun; Anar, Ceyda; Özdoğan, Yasemin; Yalnız, Enver; Çırak, Ali Kadri; Erbaycu, Ahmet Emin
    Amaç: Göğüs hastalıkları hastanesi acil servisine başvuran onkoloji hastalarının genel özelliklerini ortaya koymak amaçlandı. Yöntem: Bir aylık dönemde acil servise başvuran malignite tanılı hastaların sosyodemografik verileri ile birlikte başvuru semptomları ve acil tanıları retrospektif olarak incelendi.Bulgular: Çalışmaya alınan 118 hastanın 105 (%84.7)’si erkek, 13 (%15.3)’ü kadın ve yaş ortalaması 61.2 yıl idi. En sık başvuru yapan yaş aralığı 50-59 idi. Hastalarımızda saptanan en sık semptomlar nefes darlığı (%50), ağrı (%27.9), ateş (%14.4) ve hemoptizi (%10.1) idi. Daha az sıklıkta bulantı (%9.3), öksürük-balgam çıkarma (%7.6) ve halsizlik (%5.9) izlendi. Küçük hücreli dışı akciğer karsinomlu hastaların %87.5’i ve küçük hücreli akciğer karsinomunun %23.5’i ileri evre kansere sahip idi. En sık rastlanan acil tanı 49 (%41.5) hastada solunum yetmezliği, 14 (%11.8) hastada kemik metastazı, 13 (%11) hastada beyin metastazı idi.Sonuç: Göğüs hastalıkları acil servisine başvuran hastaların en sık yakınmaları nefes darlığı ve ağrı, en sık acil tanıları solunum yetmezliği ve metastatik hastalıktır. Genel talep palyatif tedaviler içindir, ölüm oranı düşüktür.