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    Concomitant Chest Wall Resection and Reconstruction in a Cohort of 254 Patients of Non-small Cell Lung Cancer Resections Between 2007 and 2019: a 12-Year Experience from a Single Center in Turkey
    (Springer India, 2023) Batihan, Guntug; Ucvet, Ahmet; Yazgan, Serkan; Ceylan, Kenan Can; Gursoy, Soner; Kaya, Seyda Ors
    Lung cancer with chest wall invasion, which constitute 5-10% of operable non-small cell lung cancer cases, is heterogeneous in terms of factors that may affect the prognosis. We aim to share our experience including the surgical results of patients with non-small cell lung cancer (NSCLC) who underwent chest wall resection and identify the potential factors that may impact survival. The patients who underwent combined chest wall and lung resection due to primary lung cancer invading the chest wall in our center between 2007 and 2019 were reviewed. Variables such as age, tumor size, histological subtype, surgical technique, depth of invasion, the extent of resection, neoadjuvant, and adjuvant treatment status were examined. Two hundred fifty-four patients who underwent combined chest wall and lung resection were included in the study. There were 245 men and 9 women. The mean age was 61.0 SD8.4 years. The overall survival was 70.9 SD4.6 months, and the 5-year survival rate was 41.5 SD3.3%. In multivariate analyses, age, the extent of lung resection, the number of resected ribs, invasion depth, and completeness of chest wall resection were independent factors that have an effect on survival. This study shows that age, the extent of lung and chest wall resection, invasion depth, and completeness of chest wall resection are independent prognostic factors of survival in patients who underwent combined lung and chest wall resection for NSCLC. Institutional Review Board of the Dr Suat Seren Chest Diseases and Surgery Medical Practice and Research Center (No: E-49109414-604.02.02).