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    Evaluation of alveolar-capillary membrane functions by thoracic ultrasonography in heart failure
    (2024) Gurses, Ecem; Zoghi, Mehdi
    Objectives: This study aimed to research the effect of the increased B-line count (interstitial fluid accumulation) in patients with congestive heart failure on the diffusion capacity of the alveolar-capillary membrane. Patients and methods: This prospective study was conducted with 77 inpatients diagnosed with pulmonary edema and decompensated heart failure between January 2018 and December 2018. The B-line counts of the patients were calculated through echocardiography and thoracic ultrasonography within the first 24 h of their admission, and the patients were categorized into two groups based on their B-line counts being <15 (n=26; 18 males, 8 females; mean age: 48.6±3.3 years; range, 21 to 72 years) or >15 (n=51; 36 males, 15 females; mean age: 53.7±2.0 years; range, 20 to 79 years). After sufficient diuretic treatment, the patients who were able to tolerate and pass the tests were then subjected to a respiratory function test, diffusion test [DLCO (diffusing capacity of the lungs for carbon monoxide)], and six-minute walk test (6MWT). Results: The following results in study were found in the echocardiography of the patients with a B-line number >15: lower right ventricular ejection fraction (p=0.003), lower right ventricular systolic motion (p=0.014), higher systolic pulmonary artery pressure (p<0.0001), higher tricuspid regurgitant velocity (p=0.001), more dilated vena cava inferior radius (p<0.0001), higher left atrium volume (p=0.007), higher early diastolic transmitral flow velocity/early diastolic mitral anullar velocity (E/e´) >15 (p<0.0001), and higher pleural effusion (p=0.014). The following results were found in the respiratory function test, DLCO test, and 6MWT of the patients with a B-line number >15: lower forced vital capacity (p<0.0001), lower forced expiratory volume in 1 sec (p=0.002), lower corrected DLCO (p<0.0001), lower 6MWT (p<0.0001). Conclusion: B-line counts >15 may be a predictor of a decrease in diffusion capacity, restrictive pattern in respiratory function, decrease in right ventricular function, and increase in pulmonary vascular resistance.
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    Öğe
    Myocardial bridge and beta blockers: effect on left ventricular strain parameters
    (Taylor & Francis Ltd, 2023) Yurdam, Ferhat S.; Gurses, Ecem
    ObjectivesTo assess the effect of beta-blocker treatment on left ventricular global longitudinal strain (LV Gls) as measured by echocardiography in patients with MB (Myocardial Bridge).Patients and methodsBetween January 2019 and February 2022, a prospective, single-center study was undertaken in which myocardial bridging was identified in individuals who had coronary angiography. One hundred patients with myocardial bridging were systematically recruited and strain echocardiography was performed. Patient data were analysed in two groups - those who weren't using beta-blockers in the last six months (Group I: n = 50) vs. those who were (Group II: n = 50).ResultsOne hundred patients participated in the study (38 females, 62 males; average age: 57.4 years). There was a statistically significant difference in the mean heart rate between groups I and II (p < 0.001). LV Gls was found to be statistically significantly improved in favour of group II when compared to group I [Group I: (-12.57)+/- 3 vs. Group II: (-15.92)+/- 2.9, p < 0.001].ConclusionThe negative chronotropic effect of beta-blocker medication in individuals with MB identified by coronary angiography has a beneficial effect on LV Gls as measured by echocardiography.