Yazar "Gok, Kadir" seçeneğine göre listele

Listeleniyor 1 - 6 / 6
  • Küçük Resim Yok
    Öğe
    Artificial Intelligence Supported Design of Biomedical Materials and Devices
    (CRC Press, 2024) Gok, Kadir
    Biomedical Engineering is an interdisciplinary field at the intersection of engineering, biology, and medical sciences. It includes the development of processes, devices, and procedures used in the diagnosis and treatment of medical conditions, aiming to provide efficient and effective healthcare services. This field relies on collaboration between engineers, scientists, and medical professionals to address complex challenges. Biomaterials, an essential component of biomedical engineering, are materials designed for use in contact with biological systems. They find applications in various medical areas, including implants, diagnostic devices, and tissue engineering. Biomaterials play a crucial role in advancing medical technology and have a significant presence in the global market. This chapter explores the definition and working areas of biomedical engineering, biomechanics, biomaterials, biomedical devices, medical imaging systems, and the integration of artificial intelligence in biomedical material and device design. By discussing these topics, we provide insights into the diverse applications of biomedical engineering and highlight the role of interdisciplinary approaches in improving healthcare outcomes. The chapter aims to serve as a comprehensive resource for researchers, professionals, and students interested in the field, fostering further advancements in biomedical engineering and its related disciplines. © 2025 Mustafa Berktas, Abdulkadir Hiziroglu, Ahmet Emin Erbaycu, Orhan Er and Sezer Bozkus Kahyaoglu.
  • Küçük Resim Yok
    Öğe
    CAN BE A PREFERABILITY BETWEEN INDUCTION ANESTHETIC AGENTS FOR FRACTURE SURGERY. HISTOPATHOLOGICAL AND BIOMECHANICAL APPROACH ON RATS
    (World Scientific Publ Co Pte Ltd, 2023) Kuyubasi, Sabit Numan; Inal, Canan; Inal, Sermet; Inal, Mehmet Turan; Deger, Aysenur; Gok, Kadir; Oner, Suleyman Kaan
    As the effect of many medical agents such as nonsteroidal anti-inflammatory drugs or antibiotics were investigated on bone fracture healing, there is no study about the anesthetic agents when compared histopathologically and biomechanically. We asked the question that if a superiority can be between them since we operate many fractures and see the delayed or nonunions. Although different anesthetic agents are used in general anesthesia, the effects of these substances on bone fracture healing are not clear. Here, we intended to research different anesthetic agents on fracture union in rats. The study was done between January 2020 and November 2021 in a university animal research laboratory. Totally 48 male Wistar-Albino rats weighing 250-300g were seperated into 3 groups as Tiyopental Na in Group 1, Ketamin in Group 2 and Propofol in Group 3. For anesthesia; 40, 100, 100mg/kg of single dosages were injected intraperitoneally, respectively. A shaft fracture was created bilaterally to the tibia of all rats. Kirschner (K) wire is used for the fixation of fractures. Biomechanical and histopathological examination in bones is performed at the end of the first and second months in terms of fracture healing. It has been found that the fracture union in group 1 was statistically signifigant higher than group 3 at the end of the first and second months histopathologically (P = 0.006, P = 0.002). It is also found there is a statistically significant difference between groups 1 and 3 after the second month biomechanically (P = 0.013). Although the union was higher in group 1 than group 2 histopathologically and biomechanically after the first and second months, there was no statistically significant difference (P = 0.376, 0.039; P = 0.028, 0.867). There was a general trend in the decrease of union measurements starting from group 1 to 3 at the end of the first and second month both histopathologically and biomechanically. In this study, it is found that there was a positive consistency between histopathological and biomechanical results with respect to bone union. They supported each other. Fracture healing is stronger in rats that were anesthetized by using thiopental than those using ketamine and propofol, we think that this may affect the choice of anesthetic agent and further studies are needed.
  • Küçük Resim
    Öğe
    Computer aided analysis of biomechanical performance of schanz screw with different additive manufacturing materials used in pertrochanteric fixator on an intertrochanteric femoral fracture (corrosion resistance approach)
    (Wiley, 2023) Gok, Arif; Urtekin, Levent; Gok, Kadir; Ada, H. Deniz; Nalbant, Asrin
    This study examines the use of computer-aided analysis to evaluate the biomechanical performance of Schanz screws made from different additive manufacturing materials (Ti6Al4V, 316 L, Inconel 625, and Inconel 718) in a pertrochanteric fixator for the treatment of intertrochanteric femoral fractures. Intertrochanteric fractures (ITFs) are severe traumas often seen in the elderly population and can lead to serious consequences. The primary objective of ITF surgery is to provide stability and allow for early ambulation and rehabilitation. The Pertrochanteric Fixator is a surgical implant used to treat hip fractures near the greater trochanter, and is attached to the femur with screws. The procedure is performed under general anesthesia and typically takes 1-2 h. Possible complications include infection, nerve injury, and hardware failure. The aim of this study is to evaluate the biomechanical performance of Schanz screw using computer-aided analysis, comparing the effects of various additive manufacturing materials including Ti6Al4V, 316 L, Inconel 625 and Inconel 718 in a pertrochanteric fixator for intertrochanteric femoral fractures. Additionally, this study will also consider the corrosion resistance of these materials to ensure long-term durability and effectiveness in a clinical setting. The stress values mentioned for the implant materials are as follows. Ti6Al4V: 153.33 MPa, 316 L: 180.98 MPa, Inconel 625: 158.94 MPa, Inconel 718: 148.91 MPa. Higher stress values indicate a greater load transfer to the bone, which can potentially lead to stress shielding. Stress shielding occurs when an implant bears a significant portion of the load that should be transferred to the bone. This reduced stress at the fracture site can prevent the healing process, as bones require adequate stress levels for optimal remodeling and regeneration.
  • Küçük Resim Yok
    Öğe
    Investigating the corrosion relationship and biomechanical effectiveness of Ti6Al4V screws Coated hBN and HA in triangular configuration for femoral neck fracture fixation using 3D modeling and numerical analysis
    (Sage Publications Ltd, 2025) Gok, Kadir; Gok, Arif
    This study investigates the biomechanical behavior and corrosion resistance of Ti6Al4V screws coated with hexagonal boron nitride (hBN) and hydroxyapatite (HA) for femoral neck fracture fixation using a triangular configuration under axial loading. Utilizing 3D modeling software (Geomagic Studio and SolidWorks) and numerical analysis with AnsysWorkbench, the screws were designed and analyzed. The study aimed to determine the biomechanical effects and corrosion relationships of Ti6Al4V coated with hBN and HA. Comparative analysis revealed that Ti6Al4V-HA exhibited higher gap (0.036427), penetration (0.0028631), and sliding distance values (0.0024398) compared to Ti6Al4V-hBN (gap: 0.036196, penetration: 0.0028579, sliding distance: 0.0024300), indicating greater reactivity and corrosion potential. Conversely, Ti6Al4V-hBN demonstrated superior corrosion resistance. The findings suggest that hBN-coated Ti6Al4V screws provide improved stability and reduced stress concentration, which are critical for successful fracture fixation. Additionally, hBN coating effectively reduced the corrosion rate of Ti6Al4V in simulated body fluids, enhancing implant longevity and patient safety. However, further in vivo studies are necessary to validate these findings and assess long-term performance and biocompatibility. The study underscores the need to consider multiple factors in implant material selection to gain a comprehensive understanding of corrosion behavior. Overall, this research lays the groundwork for future advancements in orthopedic implant technology and has the potential to improve patient outcomes in fracture management.
  • Küçük Resim Yok
    Öğe
    INVESTIGATION OF THE EFFECT OF ELBOW PIPES OF TI6AL4V, 304 STAINLESS STEEL, AZ91 MATERIALS ON EROSION CORROSION BY FINITE ELEMENT ANALYSIS
    (Czech Technical Univ Prague, 2024) Gok, Kadir; Danismaz, Merdin; Urtekin, Levent; Ada, Hediye Deniz; Gok, Arif
    Corrosion is the degradation of metals caused by chemical or electrochemical reactions with their environment. As a result of these reactions, undesirable conditions occur in the physical, chemical, mechanical and electrical properties of metals. These conditions cause parts made of metallic materials to become unusable. Erosion corrosion is one of the most common types of corrosion in fluid transfer. There are several methods for preventing erosion corrosion. First of all, some precautions should be taken to prevent wear. Intervention is very important in terms of cost, especially at the design stage. Measures such as wide angle bends, wall thickness of wear-resistant material and corrosion allowance can be taken, especially in applications where the flow direction needs to be changed. The aim of this study was to determine the effect of liquid fluid on erosion corrosion in Ti6Al4V, 304 stainless steel and MgAz91 elbow pipes by using the computer aided and finite element based AnsysWorkbench Explicit Dynamics module. For the design of the elbow pipe, SolidWorks was used for 3D studies. In the analysis of the pipe, the suitability of the pipe for the 3D model was examined. The effect of fluid rotation on the pipe walls and the effect of the pipe material on the flow along the pipe were determined. The standard k-e model based on the velocity-pressure relationship in continuous and steady flow was used for the flow calculations. The flow simulation showed that for all models the flow accumulation after rotation was more concentrated on the opposite walls of the pipe, as expected. The results obtained showed that the deformation in MgAZ91 material had the highest value at 9.14 x 10-8 mm. This situation has been interpreted to mean that it may vary depending on the flow rate automation. Designs on the old designs in the erosion structure of the liquid that occurs in the pipes with a new product design in the analysis design.
  • Küçük Resim Yok
    Öğe
    The Biomechanical Performance of Implant Screws with Different Biomaterials in Orthopedic Bone Fixation Procedures
    (Springer India, 2024) Gok, Kadir; Gok, Arif
    This study aimed to investigate the bone screwing process for stabilization following reduction of femur shaft fracture using M3.5 cortex screws made of four different materials: 316L stainless steel, Ti6Al4V, NiTi, and WC. The numerical analysis was performed using the finite element method and Deform-3D software, with loading and boundary conditions being accurately identified for each analysis. The screwing moment, screw wear, and temperature distributions in both the screw and bone material were evaluated for each material during the screwing process. The results showed that the lowest bone temperatures were achieved when using WC screws, followed by 316L, Ti6Al4V, and NiTi screws. The numerical simulations demonstrated good consistency across all four screw materials during the bone screwing process. The study used Finite Element Analysis to simulate screw insertion into sawbones. It employed tetrahedral elements for meshing, focusing on the hole area to mimic screwing accurately. Sawbones' lateral surfaces remained fixed, while the screw model experienced different spindle speeds and a constant feed rate. Contact between screw and sawbones was established using a master-slave algorithm, considering a friction coefficient of 0.42 to simulate frictional forces.