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Öğe Evaluation of whether smoking cessation among advanced lung cancer patients has a significant effect on anxiety and depressive symptoms(Kare Publ, 2023) Guldaval, Filiz; Polat, Gulru; Anar, Ceyda; Ayranci, Aysu; Karadeniz, Gulistan; Gayaf, Mine; Turk, Merve AyikBACKGROUND AND AIM: Continued smoking has a detrimental effect on lung cancer patients, which may already be associated with anxiety and depression. There is a belief among some that smoking cessation will further increase anxiety and depression in these patients, reducing their quality of life. In this study, we aimed to determine whether there was a difference in anxiety, depression, and quality of life scores between ex-smokers after the diagnosis of lung cancer and current smokers.METHODS: One hundred patients with advanced lung cancer were included in the study. Demographic characteristics were recorded, and the smoking status of patients was questioned. The Hospital Anxiety and Depression Scale and European Organization for Research and Treatment of Cancer Quality of Life tests were performed to evaluate anxiety, depression, and quality of life.RESULTS: The mean age was 61 & PLUSMN;8 years. Adenocarcinoma was the most common type of cancer, and 64% of the cases were at stage 4. Of the total 100 patients, 8 had never smoked, 23 were smokers, and 69 were ex-smokers. After the diagnosis of lung cancer, 17 patients quit smoking. No statistically significant difference was found between smoking status and anxiety or depression and quality of life scores (p>0.05). There was no difference between anxiety or depression and quality of life scores between patients who quit smoking after the diagnosis and those who continued (p>0.05).CONCLUSIONS: Patients with lung cancer should not be abstained from smoking cessation because of the possibility of increased anxiety or depression; rather, patients should be supported for smoking cessation at any stage.Öğe Pneumothoraxes after CT-guided percutaneous transthoracic needle aspiration biopsy of the lung: A single-center experience with 3426 patients(Turkish Assoc Tuberculosis & Thorax, 2023) Polat, Gulru; Ozdemir, Ozer; Unat, Damla Serce; Karadeniz, Gulistan; Ayranci, Aysu; Unat, Omer Selim; Buyuksirin, MelihIntroduction: The purpose of this study is to determine how long patients who developed pneumothorax were followed up on in the emergency department, how many patients required chest tube placement, and what factors influenced the need for a chest tube in patients who underwent computed tomography (CT)-guided percutaneous trans -thoracic fine needle aspiration biopsy (PTFNAB).Materials and Methods: Patients who developed pneumothorax following CT-guided PTFNAB were analyzed retrospectively. In cases with pneumotho-rax, the relationship between chest tube placement and the size of the lesion, the lesion depth from the pleural surface, the presence of emphysema, and the needle entry angle were investigated. It was determined how long the patients were followed up in the emergency department, when a chest tube was pla-ced, and when patients who did not require chest tube placement were discharged.Results: CT-guided PTFNAB was performed in 3426 patients within two years. Pneumothorax developed in 314 (9%) cases and a chest tube was placed in 117 (37%). The risk factor for chest tube placement was found to be the lesion depth from the pleural surface. The lesion depth from the pleural surface of >24 mm increased the risk of chest tube placement by 4.8 times. Chest tubes were placed at an average of five hours (5.04 +/- 5.57).Conclusion: This study has shown that in cases with pneumothorax that required chest tube placement, the lesion depth from the pleural surface is a risk factor. Patients who developed pneumothorax on CT during the procedure had chest tubes placed after an average of five hours.Öğe Risk Factors for Presence of Resistant Microorganisms in Sputum Cultures of Patients with Infectious Exacerbations of Chronic Obstructive Lung Disease(Bilimsel Tip Yayinevi, 2022) Buyuksirin, Melih; Senol, Gunes; Polat, Gulru; Ayranci, Aysu; Guldaval, Filiz; Serce Unat, DamlaIntroduction: Antibiotics reduce the risk of short-term mortality. Certain bacteria may be resistant to initial regimens which is related to mortality. The aim of this study was to find risk factors for the presence of resistant bacteria during exacerbation of Chronic Obstructive Pulmonary Disease (COPD). Materials and Methods: Ethics committee approval was obtained for the study. The patients hospitalized with an exacerbation of COPD between 2015 and 2020 were retrospectively ieviewed. The patients with a sputum culture result were divided into: Group A with conventional microorganisms (susceptible to initial antibiotic regimen) and Group B with non-conventional microorganisms (resistant to initial antibiotic regimen). The risk factors for Group B microorganisms were investigated. Results: One hundred and nineteen patients were included in the study. Median age was 68 (40-88) years. There were 22 patients in Group A and 97 in Group B. Most common microorganism in Group A was Haemophilus influenza (12.6%). Most encountered microorganisms in Group B were Pseudomonas aeruginosa (49.6%). Male sex (HR= 2.9; 95% CI= 0.9-9.5; p= 0.073), age >61 (HR=4.8; 95% CI= 1.7-13.6; p= 0.003), and >5 hospitalizations last year (HR= 8.2; 95% CI= 0.9-67.7; p= 0.051) were found to be independent risk factors for resistant microorganisms. Conclusion: Proposed risk factors for the isolation of multidrug resistant microorganism in patients hospitalized with COPD exacerbations should be considered when choosing the initial antibiotic regimen.