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    Acute mesenteric ischemia in the surgical intensive care unit: Analysis of clinical characteristics and risk factors for mortality
    (2023) Kızıloğlu, İlker; Daylan, Ahmet; Şener, Aslı; Aygün, Hakan; Bozok, Şahin
    Objectives: This study aimed to present the clinical characteristics of patients followed due to acute mesenteric ischemia (AMI) in the surgical intensive care unit and evaluate mortality-related prognostic factors. Patients and methods: This retrospective study reviewed clinical records of 28 patients (19 males, 9 females; mean age: 67.5±17 years; range, 29 to 86 years) who were followed due to AMI in the intensive care unit between May 2016 and April 2023. We analyzed the clinical characteristics, risk factors, and prognostic factors of the patients. The Acute Physiology and Chronic Health Evaluation II (APACHE II) score was calculated in each patient to assess its prognostic value in AMI patients. Results: Of the 28 patients, 19 had acute arterial occlusive mesenteric ischemia (AOMI), four patients had acute mesenteric venous thrombosis (MVT), and five patients had nonocclusive mesenteric ischemia (NOMI). Overall mortality was 60.7% (n=17). The mortality rate was 57.8% (n=11) in the AOMI group, 50.0% (n=2) in the MVT group, and 80.0% (n=4) in the NOMI group. Compared to survivors, the APACHE II score, shock incidence, arterial lactate concentration, specifically more prominent 24 h after diagnosis (p<0.001), acute renal failure, serum creatinine level, vasoactive agent consumption, and maximum vasopressor dose were significantly higher among nonsurvivors (p<0.05). Conclusion: The clinical outcomes remain poor in AMI, and even in-hospital mortality is rather high. The death following AMI was mostly related to multiorgan failure, renal failure, elevated lactate level, and colon involvement. It appears that monitoring arterial lactate is helpful in identifying patients with poor prognosis. Early diagnosis, timely treatment, correction of shock, and renal protection are important to improve clinical prognosis.
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    An innovative method to prevent infection when measuring the arterial blood gas SpO2 saturation
    (German Medical Science-Gms, 2024) Şahan, Seda; Guler, Sevil; Gectan, Eliz; Aygün, Hakan
    Background: Patients are hospitalized for extended periods, particularly in intensive care units (ICUs). As a result, the saturation probe (pulse oximeter) remains attached for an extended period and microorganisms can grow in the wet environment. If the pulse oximeters are not reprocessed, cross -infection may occur. The literature contains several studies in which gloves were used for the measurement while various SpO2 (peripheral arterial oxygen saturation) measurements were compared with each other. However, such comparisons have yet to be made with the results of arterial blood gas SpO2 measurements by pulse oximeter, considered as the gold standard. The present study aimed to compare arterial blood gas values with the fingertip saturation measurement performed by having adult patients wear gloves of different colors, one after the other, on their fingers and determining the effect of the differently colored gloves (transparent, white, black, light blue) on saturation values. Methods: The study was conducted on 54 patients in an ICU. Intra-arterial blood gas SpO2 results were measured. Oxygen saturation was measured while the patient 1. did not wear gloves and 2. sequentially wore a series of gloves of different colors. Paired t -test, correlation analysis, and Bland Altman charts were used to evaluate the results. Results: The mean SpO2% value of the participants' intra-arterial blood gas measurements was 97.76 +/- 2.04. The mean SpO2% value obtained from the measurements of the fingers with a transparent glove was 0.43 points lower than the mean SpO2% value of the intra-arterial blood gas measurements (t=0.986, p=0.61). The mean SpO2% value obtained from the measurements of the fingers with a white glove was 0.93 points lower than the mean SpO2% value of the intra-arterial blood gas measurements (t=1.157, p=0.093). Conclusion: Of the measurements performed with a glove, the mean SpO2% value obtained from the measurements of the fingers with a transparent glove was more consistent with the mean SpO2% value of the intra-arterial blood gas measurements than measurement of the fingers without a glove.
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    Association between Anesthesia Management and Preoperative Magnetic Resonance Image Quality in Patients Scheduled for Deep Brain Stimulation Surgery
    (Tıbbi Kayıtlar Derneği, 2023) Bilgin, Sezgin; Aslan, Kerim; Turunç, Esra; Dost, Burhan; Aygün, Hakan; Köksal, Ersin
    Aim: To investigate magnetic resonance image quality and the number of motion artifact-related repeated sequences based on anesthesia or sedation management during preoperative MR imaging for DBS surgery. Material and Methods: The medical records of patients who underwent DBS procedures at the hospital of Ondokuz Mayis University, between April 2011 and October 2021 were retrospectively analyzed. Age, gender, and diagnosis information were recorded for each case. Patients were grouped into general anesthesia, sedation, no sedation groups. The evaluation of magnetic resonance images was performed by a specialized in neuroradiology. The radiologist classified the image quality as good, moderate, or poor based on artifacts resulting from unwanted motion. Results: A total of 127 patients, out of 190 patients, were included in the study. There were no significant differences in image quality based on anesthesia/sedation method and airway management (p>0.05). No significant differences were observed in the number of repeated sequences when compared based on anesthesia/sedation method and airway management (p>0.05). Conclusion: General anesthesia, sedation, or no sedation during preoperative magnetic resonance imaging in patients with movement disorders did not result in significant differences in image quality and the number of sequences requiring repetition.
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    Comparison of forearm and intra-arterial blood pressure measurements according to body and arm positions in obese patients
    (Wiley, 2025) İsmailoğlu, Elif Günay; Aygün, Hakan; Şahan, Seda; Ergin, Eda; Geçtan, Eliz
    RationaleNoninvasive blood pressure (BP) monitoring is very important also difficult for accurate diagnosis and monitor of obese patients.AimsThe study aimed to assess the agreement between forearm arm BP and intra-arterial BP values in a different body and arm positions in obese patients.MethodsThe descriptive study was carried out on 60 intensive care patients with a body mass index above 30 kg/m2 who were monitored with invasive radial BP in the general and surgical intensive care units. BP values obtained from the upper arm and forearm with different arm and body positions were compared with intra-arterial BP results. Bland-Altman analysis and correlation coefficient were used for the accuracy of upper and forearm noninvasive BP reading in different positions.ResultsThe best agreement was found between the forearm systolic BP in the supine and half-sitting position with the arm down and intra-arterial BP values. Also, the best agreement in diastolic BP was found between the half-sitting and half-sitting position with the arm down and intra-arterial BP.ConclusionsForearm systolic BP measurement, especially in the supine and half-sitting position with the arm below the heart level position, was best agreement with intra-arterial measurement, regarded as the gold standard. For this reason, it is more appropriate to use forearm BP measurement in obese patients monitored in intensive care to obtain accurate results.
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    Determination of anthropometric measurements that may be associated with difficult incubation in children
    (2022) Kutlucan, Leyla; Aygün, Hakan
    Aim: Difficult tracheal intubation is a fundamental cause of perioperative morbidity and mortality. The frequency of difficult intubation is thought to be higher in the pediatric age group due to the different anatomical and physiological structures, and it may not be easy to detect this beforehand. Anthropometric measurements were evaluated before the elective operation and the relationship of some parameters with difficult intubation. Material and Method: This prospective cross-sectional study was conducted on 90 pediatric patients aged 2-14 who underwent elective surgery under general anesthesia. All patients’ age, gender, height, weight, body surface area (BSA), and body mass index (BMI) records were recorded before the operation. Mallampati scoring, head and neck circumference, thyromental distance measurements, and head circumference/neck circumference ratio were performed. Cormack-Lehane (CL) scoring and endotracheal intubation were applied during direct laryngoscopy of the operated patients. Children with easy intubation (CL grade 1 and 2) group 1; children who underwent difficult intubation (CL grade 3 and 4) were defined as group 2. Results: There was no significant relationship between Groups I and II in terms of age, height and weight values. There was no significant relationship between the two groups with BSA and thyromental distance measurements. Mallampati scores were found to be grades 3 and 4 (3.3%) in three of the 90 patients, and CL scores of 3 and 4 (4.4%) in four patients. A significant correlation was found between Mallampati scoring and CL scoring. A statistically significant difference was found between the two groups regarding head/neck ratios and BMI. Conclusion: In our study, head circumference/neck circumference ratio and BMI were found to be helpful while predicting difficult intubation in children with normal physical characteristics, 2-14 years of age, who underwent elective surgery. Our findings can be supported by further studies that will be planned and include more patients.
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    Does preoperative gum chewing reduce postoperative sore throat?
    (W.B. Saunders, 2025) Okgün Alcan, Aliye; Akdağ, Dilek; Aygün, Hakan; Kebabçı, Eyüp
    Purpose: There are numerous pharmacological and nonpharmacological methods that are used to manage postoperative sore throat (POST). The purpose of this study was to compare the efficacy of different types of herbal gums on POST management. Design: A randomized controlled, blinded, prospective, experimental study. Methods: This study was carried out between June and October 2023 in a research and training hospital. A total of 72 patients scheduled for cholecystectomy were randomly assigned to one of four groups in the preoperative period: control, mastic, xylitol, and propolis groups. No intervention was applied to the control group, while patients in the experimental groups chewed either mastic-flavored, xylitol, or propolis gum. Patients in the experimental groups chewed sugar-free gum for 15 minutes immediately before surgery. The incidence and severity of sore throat were evaluated upon admission to the postanesthesia recovery unit and at the 1st, 2nd, 6th, and 24th hours postoperatively. Descriptive statistics, χ2, Fisher's Exact, Independent samples t test, and Kruskal-Wallis tests were used in the analysis of the data. Findings: There was no significant difference in POST severity between the groups at admission to the postanesthesia recovery unit and at the 1st, 6th, and 24th hours postoperatively. However, the rate (P: .007) and the median POST score (P: .046) in the propolis group were significantly lower than that of the other groups at the 2 hours postoperatively. Additionally, throat dryness in the propolis group was significantly lower at the first (P: .046) and second (P: .023) hour after surgery compared to the other groups. Conclusions: Preoperative chewing sugar-free gum containing propolis effectively reduces sore throat and throat dryness within the first 2 hours after surgery. © 2025 The American Society of PeriAnesthesia Nurses
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    The effect of neutrophil lymphocyte ratio on mortality in patients followed in the intensive care unit with the diagnosis of ischemic stroke from the emergency department
    (2022) Aygün, Hakan; Şener, Aslı
    The goal of this study was to determine if the neutrophil-lymphocyte ratio (NLR) predicts mortality in patients hospitalized in the intensive care unit (ICU) with an ischemic stroke. Between January 1 and December 31, 2021, 116 patients admitted to our emergency department with the diagnosis of ischemic stroke and hospitalized in the 3rd level ICU unit were included in the study and divided into two groups: patients who died (Group 1: n=62) and patients who survived (Group 2: n=54). Patients’ age, gender, presence of chronic diseases, Acute Physiology and Chronic Health Evaluation (APACHE) II score, and neutrophil count, lymphocyte count, and NLR were obtained by dividing these two numbers in the first complete blood count taken at the time of admission to the emergency department were collected and analyzed. While 54 (46.5%) patients were discharged from the ICU, 62 (53.4%) patients died. 60 (51.7%) of the patients were female. The average age of patients was 76.85±10.70. APACHE II score was found to be correlated with mortality (AUC 0.70, 95% CI (0.616-0.802) (p=0.01). When the APACHE II cut-off value was more than 13.5, it predicted mortality with 95% sensitivity and 85% specificity. The median NLR ratio of the patients was found to be 5.08 (0.38-35.16) in the survivors and 11.68 (1.38-113.00) in patients that died. NLR was lower in survivors (p=0.002). NLR may be a valuable marker in predicting mortality in stroke patients admitted to the ICU.
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    Innovation in measuring obese patients' blood pressure: measurement with conical wrapping technique
    (Lippincott Williams & Wilkins, 2022) Şahan, Seda; Şahin, Sevil; Aygün, Hakan; Yıldız, Aysegül
    Introduction Accurate measurement of blood pressure (BP) is difficult in obese patients due to their upper arm shape and width. Errors made during BP measurement cause misdiagnosis or lead to wrong treatment. Method The data of this methodological study were collected from 40 patients who were 18 years old or above, with a BMI above 25 kg/m(2), and who were followed up with radial catheter arterial pressure in adult intensive care and postoperative care units between March and December 2020. Results In total 55% of the participants were male with a mean age of 63.9 years, mean height of 165.7 cm, mean weight of 85.2 kg and mean BMI of 31.0 +/- 2.1 kg/m(2). Intra-arterial BP (IABP) measurement values were found to be correlated with conical wrapping technique and cylindrical wrapping technique (P < 0.001). As a result, a statistically significance was found between conical SBP and intra-arterial SBP (r = 0.921; P < 0.05) and conical DBP and intra-arterial DBP (r = 0.902; P < 0.05) Conclusion It was determined that the SBP and DBP results of the conical wrapping technique were closer to the results obtained by IABP measurements. For this reason, it is more appropriate to measure BP with conical wrapping technique in clinically obese patients.
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    Use of ultrasound guided single shot costotransverse block (intertransverse process) in breast cancer surgery: a prospective, randomized, assessor blinded, controlled clinical trial
    (Bmc, 2022) Aygün, Hakan; Kızıloğlu, İlker; Öztürk, Nilgün Kavrut; Öcal, Haydar; İnal, Abdullah; Kutlucan, Leyla; Gönüllü, Edip
    Background: Ultrasound guided costotransverse block (CTB) is a relatively newperi-paravertebral block that has been described recently. It has been previously reported that CTB, administered with a single high-volume injection, provides effective analgesia in breast conserving surgery. In this study we evaluated the effect of CTB when used in breast cancer surgery. Methods: Seventy patients due to undergo breast cancer surgery were included in this blinded, prospective, randomized, efficiency study. Patients were randomized into two equal groups (CTB group and control group) using the closed envelope technique. All patients underwent general anesthesia. In addition to standard analgesia methods, patients in group CTB also received CTB block while the remaining (control group) did not. Numeric rating (pain) scores and opioid consumption was compared between the two groups. Results: Opioid consumption in all time frames and pain scores at 1st and 3rd hours only were found to be significantly lower in Group CTB when compared to the control group. Conclusions: Ultrasound guided CTB improves analgesia quality in breast cancer surgery.

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