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    Metastatic salivary gland mammary analogue secretory carcinoma (MASC) of parotid gland - A rare case report in the literature review
    (Taylor & Francis Ltd, 2023) Aliyeva, Aynur; Karimov, Ziya; Müderris, Togay
    We present a patient diagnosed with a parotid tumor whose histopathology was MASC. A 58-year-old female presented with a 5-month history of an enlarging right parotid mass. Ultrasonography showed a 48 x 30 mm heterogeneous solid lesion with a lobulated contour in the right parotid gland. A neck computed tomography (CT) with intravenous (IV) contrast showed a 28 x 34 mm pathological mass in the right parotid gland. After FNA, parotidectomy, and modified radical neck dissection, pathology showed that the surgical margin was positive for tumor, and one lymph node was metastatic in the right neck. This case was classified as T2N1M1 staged MASC of the salivary gland. She completed seven weeks of radiation therapy (RT) after surgery, and no recurrence or metastasis was observed at the 32nd-month follow-up. We aimed to report a rare parotid gland tumor with this case and inspire new research on diagnosing and treating rare salivary gland tumors
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    Pediatric Bell’s palsy: prognostic factors and treatment outcomes
    (2020) Ayşel, Abdulhalim; Yılmaz, Mehmet Fatih; Tokat, Taşkın; Aliyeva, Aynur; Altaş, Enver; Müderris, Togay; Şimşek, Özgür Özdemir
    Background. Idiopathic facial paralysis or Bell’s palsy is the most common type of peripheral facial paralysis. Children with Bell’s palsy is an uneasy situation for the family and physician with questions about the etiology, treatment options and the healing process. Here, we aimed to compare the epidemiologic features and prognostic factors of patients with Bell’s palsy aged <18 years.Methods. Records of patients with Bell’s palsy who were admitted to our clinic between January 2008 and December 2017 were evaluated. Results. Forty-seven patients with Bell’s palsy were included to this study. The patients’ ages varied between 7 and 17 (14.7±2.5) years. At the end of at least 6 months of follow-up, 32 (68.1%) of the patients presented with House Brackmann (HB) grade 1 facial paralysis, while 12 (25.5%) of them had grade 2 and 3 (6.4%) of them had grade 3 facial paralysis. Mean neutrophil-to-lymphocyte ratio (NLR) in patients with advanced grades (grade 4, 5, 6) was higher, compared to that of patients with grade 2 and 3 (4.10 ± 1.06 vs 1.34 ± 1.02 (p <0.001). Conclusions. In our study, the response rate to treatment was high. In differential diagnosis, congenital anomalies, malignancy, trauma, middle ear infection and surgery should be considered. In addition, NLR at admission can be considered as a prognostic factor
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    Surgical, histopathological, and clinical outcomes of parotid gland neoplasms: a 10-year tertiary single-center experience
    (2023) Aliyeva, Aynur; Agayarov, Ozlem Yagiz; Yildirim, Gokce Aksoy; Muderris, Togay; Dalgic, Abdullah
    Objectives: This study aims to contribute to the literature by presenting an overview of a 10-year experience by retrospectively examining the cases with a parotid mass from a tertiary referral center Methods: Two hundred fourteen patients were diagnosed with a parotid mass in the Otorhinolaryngology Clinic of HSU Izmir Bozyaka Training and Research Hospital between January 2009 and January 2019. Sociodemographic characteristics, diagnostic methods, surgical operations and complications, pathology results, and long-term follow-up results were retrospectively analyzed over the patients' files. SPSS Version 21.0 computer for data analysis. Results: Of 214 parotidectomies, 140 (75%) were male, 74 (35%) were female, mean age was 55 ±14 years (15-85 years). The most common diagnoses were 87 (40.7%) pleomorphic adenomas and 48 (22.4%) Wharton tumors. The most prevalent malignant tumors were reported as 18 (8.1%) mucoepidermoid carcinoma. The main type of surgery was superficial parotidectomy, performed in 192 (90%) patients. Facial paralysis was observed in 11 (5.1%) patients as the main postoperative complication. Conclusions: Considering the histopathological diagnosis of parotid tumors, the stage and grade of the tumor, surgery is generally preferred for treatment. More males are affected than women, especially in the middle ages.