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Öğe Clinical characteristics of and services provided for patients with lymphedema referred to a physiotherapy program during the years 2009 through 2019(Mary Ann Liebert, Inc, 2021) Keser, İlke; Özdemir, Kadirhan; Ertürk, Burak; Haspolat, Miray; Duman Özkan, Tuğçe; Cam, Yağmur; Suner Keklik, SinemBackground: Lymphedema is a chronic and progressive disease whose diagnosis involves determination of clinical and demographic characteristics. The aim of this retrospective study was to analyze the clinical characteristics of patients with lymphedema and their various diagnoses. We studied patients who were referred for physiotherapy services at any point during the years 2009 through 2019. Methods: Retrospective data were collected from the files of 430 lymphedema patients. The type, cause, localization, stage, and severity of lymphedema and physiotherapy needs were analyzed and reported. Results: Primary and secondary lymphedema were observed in 18 (4.2%) and 412 (95.8%) patients, respectively. The patients' mean body mass index score was 30.66 kg/m(2). The data indicated that the most common cause of secondary lymphedema was breast cancer and its treatments (n = 196, 47.6%). Other causes were chronic venous insufficiency (CVI) (n = 140, 34%), lipolymphedema (n = 11, 2.7%), and other types of cancers (n = 65, 15.7%). According to the affected body regions, 416 patients had unilateral/bilateral upper and lower extremity lymphedema and 14 had head and neck lymphedema. The patients were followed with a home-based physiotherapy program (n = 353, 82.1%) or they underwent treatments through an outpatient program (n = 77, 17.9%). Conclusions: Most patients admitted to the clinic had a diagnosis of breast cancer and CVI. The severity and stages of lymphedema were variable. The data indicated that most patients were followed through a home-based physiotherapy program. These results may set a frame for understanding the treatment and care needs of patients with lymphedema.Öğe Comparison of trace element (selenium, iron), electrolyte (calcium, sodium), and physical activity levels in COVID-19 patients before and after the treatment(Elsevier Gmbh, 2022) Özdemir, Kadirhan; Saruhan, Ercan; Benli, Tuba Kaya; Kaya, Gözde; Meral, Orhan; Yavuz, Melike Yüksel; Şen, TeomanObjective: Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), a worldwide health problem, is the cause of 2019 coronavirus disease. This study aimed to compare the trace element (selenium and iron), electrolyte (calcium and sodium), and physical activity levels of COVID-19 patients before and after COVID-19 treatment. Method: This prospective study was conducted in patients diagnosed with COVID-19 (n = 15). Trace element (selenium and iron), electrolyte (calcium and sodium), and physical activity levels of the patients were compared before and after the treatment. Result: Most of patients had selenium deficiency (86.7 %), iron deficiency (73.3 %), calcium deficiency (66.7 %) and sodium deficiency (46.7 %) before COVID-19 treatment. The most important improvements were seen in iron deficiency (from 73.3 % to 26.7 %) and sodium deficiency (from 46.7 % to 13.3 %) after the treatment. Selenium, iron, calcium, and sodium levels of the patients were significantly higher after the treatment (p < 0.05). The patients had low physical activity before and after COVID-19 treatment. In addition, no statistically significant difference was found in the comparison of physical activity levels (p > 0.05). Conclusion: This study indicated that selenium, iron, calcium, and sodium levels and deficiencies might improve after treating patients with COVID-19. However, the results of this study showed that the physical activity levels of COVID-19 patients might remain stable and low throughout the treatment process.Öğe Determination of serum trace elements (Se, Fe, Zn), macrominerals (Ca, Na, Cl), and physical activity levels in COVID-19 patients(Dustri-Verlag Dr Karl Feistle, 2022) Özdemir, Kadirhan; Saruhan, Ercan; Meral, Orhan; Kaya, Gözde; Benli, Tuba Kaya; Bakar, Yeşim; Kızıloğlu, İlkerObjective: This study mainly aims to determine serum trace elements, macrominerals, and physical activity levels in COVID-19 patients compared to healthy con-trols. Materials and methods: This prospec-tive study was conducted among COVID-19 patients (group I, n = 20) and healthy con-trols (group II, n = 20). Serum trace element levels (Se, Fe, and Zn), macrominerals (Ca, Na, and Cl), vitamin D, ferritin, and physical activity levels were determined. Results: Of the participants in group I, 90% had Se defi-ciency, 65% had Fe deficiency, and 35% had Zn deficiency. In addition, 45% of the par-ticipants in group II had Se deficiency. There was Ca deficiency (60%), Na deficiency (40%), and Cl deficiency (30%) in COVID-19 patients. Healthy controls did not have any macromineral deficiencies. The trace ele-ment levels including Se, Fe, and Zn were not statistically significant (p > 0.05); how-ever, the micromineral levels including Ca, Na, and Cl were significantly lower between groups (p < 0.05). There were vitamin D de-ficiencies in 90% and 70% of the participants in group I and group II, respectively. Ferritin levels were significantly higher in group I than group II (p < 0.05). All the participants had low physical activity levels in group I, and 40% of the participants had low physi-cal activity levels in group II. Conclusion: This study showed that COVID-19 patients might have lower Ca, Na, and Cl levels than healthy adults. In addition, high rates of Se, Fe, Ca and vitamin D deficiencies, and ferritin lev-els may be seen in COVID-19 patients. More-over, COVID-19 patients may have low levels of physical activity.Öğe Does smart phone usage in young adults have an effect on static and dynamic balance?(Hacettepe Üniversitesi, 2024) Özdemir, Kadirhan; Dönmez, Batuhan; Zeren, Melih; Şahin, Nilay Yürekdeler; Karakurum, Eshan; Eroğlu, RumeysaObjectives: This study aimed to investigate the effects of talking and note-taking on a smartphone on static and dynamic balance. Materials and Methods: In the study, healthy young adults (n=36) were asked to maintain postural balance while standing on static and dynamic platforms in different tasks: (Task I) without using a smartphone, (Task II) while taking notes on a smartphone, and (Task III) while talking on a smartphone. Center of pressure (CoP) on mediolateral (CoPx) and anteroposterior (CoPy), CoP path length, CoParea, and trunk deviation length were used to measure static and dynamic postural balance. Results: On a static platform, CoPy and CoParea were different between the tasks (p<0.001, p=0.017). Task II and Task III impaired CoPy more than the task I (p<0.001, p=0.004). Task III affected CoParea more negatively than task II (p=0.027). CoP path length was lower in task II and task III (p<0.001). CoP path length was significantly higher in task III compared to task II (p<0.001). On a dynamic platform, there were differences in CoPy between the tasks (p=0.038). There was a difference in CoPy between task II and task III (p=0.005). The CoParea was significantly different between the tasks (p=0.023). CoParea and CoP path length was higher in task II compared to task I (p=0.035, p<0.001). Conclusion: The study showed that smartphone use during specific tasks, including talking and/or note-taking on a smartphone, could increase the risk of falls and accidents by affecting center of pressure and postural sway.Öğe Does smartphone addiction impair maximal exercise capacity in young adults?(Dokuz Eylul Univ Inst Health Sciences, 2024) Zeren, Melih; Eroğlu, Rümeysa; Şahin, Nilay Yürekdeler; Özdemir, Kadirhan; Dönmez, Batuhan; Karakum, EshanPurpose: Smartphone addiction may reduce the time allocated for physical activity participation. However, it is not known if there is a direct association between smartphone addiction and reduced exercise capacity. Our aim was to investigate whether smartphone addiction impairs maximal exercise capacity, as well as analyze its influence on the perceived benefits of exercise and physical activity habits in young adults. Material and Methods: Forty-six volunteers were evaluated by a symptom-limited incremental exercise test. Smartphone addiction of volunteers was evaluated using Smartphone Addiction Scale- Short Form. Physical activity participation and perceived benefits of physical activity participation were evaluated using International Physical Activity Questionnaire- Short Form and Exercise Benefits/Barriers Scale, respectively. Results: The prevalence of smartphone addiction was 65% in young adults. No significant association was detected between smartphone addiction and any of maximal exercise capacity metrics including test duration, maximum workload achieved in watts or maximum heart rate (p>0.05). Smartphone addiction did not correlate to physical activity participation either (p>0.05). Univariate linear regression revealed Exercise Benefits/Barriers Scale score was able to explain 41% of variance in exercise test duration and 37% of variance in maximal workload (p<0.01), and it was also correlated to physical activity level (r=0.424; p<0.01) Conclusion: Smartphone addiction did not directly translate into lower physical activity participation or worse exercise capacity. However, perception of the benefits of exercise had a great influence on physical activity and exercise capacity, which highlights the importance of increasing the awareness of the benefits of physical activity among young adults for maintaining physical health.Öğe Does venipuncture increase lymphedema by triggering inflammation or infection? An experimental rabbit ear lymphedema model study(Mary Ann Liebert, Inc, 2022) Özdemir, Kadirhan; Çıtaker, Seyit; Diker, Şeyda; Keser, İlke; Kurukahvecioglu, Osman; Uyar Göçün, Pinar; Gülbahar, ÖzlemBackground: Recent guidelines recommend avoiding venipuncture to prevent lymphedema for breast cancer patients. This study investigated whether single or multiple sterile venipuncture procedures develop a systemic inflammation or infection and increase lymphedema in the rabbit ear lymphedema model.Methods and Results: Eighteen New Zealand white female rabbits were included. The right ear lymphedema model was created by surgical procedure; then, rabbits were divided into three randomized groups. Single and multiple venipuncture procedures were applied at least the 60th day after surgery for Group I and II, respectively. Group III was a control group. C-reactive protein (CRP) and procalcitonin (PCT) levels were analyzed to determine inflammation and infection. Ear thickness measurements were applied using a vernier caliper to assess the differences in lymphedema between the ears. All rabbits were euthanized on the 90th day after surgery. Histopathological analysis was performed to evaluate lymphedema by measuring tissue thicknesses. Ear thickness measurements showed that ear lymphedema was developed and maintained with surgical operation in all groups (p < 0.05). There was no difference in the ear thickness measurements between and within-groups results (p > 0.05). CRP and PCT levels were below the lower detection levels in all groups. According to the differences of histopathological ear distances, there were significant differences within-groups for all groups (p < 0.05), and no differences were identified between groups (p > 0.05).Conclusion: This experimental study demonstrated that single or multiple sterile venipuncture procedures did not trigger infection or inflammation and did not exacerbate ear lymphedema in the rabbit ear lymphedema model.Öğe The effects of clinical and home-based physiotherapy programs in secondary head and neck lymphedema(Wiley, 2021) Özdemir, Kadirhan; Keser, İlke; Düzlü, Mehmet; Erpolat, Özge P.; Saranli, Uluc; Tutar, HakanObjectives/Hypothesis To determine the effects of complex decongestive physiotherapy (CDP) and home programs on external lymphedema, staging of lymphedema, fibrosis, and three-dimensional (3D) surface scanning and volume evaluation in head and neck lymphedema. Study Design A prospective randomized controlled study. Methods Twenty-one patients were randomly divided into three groups: CDP (n:7), home program (n:7), and control (n:7). Assessment methods were applied at baseline and 4 weeks later for all groups. MD. Anderson Cancer Center Head and Neck Lymphedema Protocol was implemented to evaluate head and neck external lymphedema, staging of lymphedema, and fibrosis. A 3D scanner and a software were used to determine and calculate the volume of the head and neck region via 3D surface scanning. Head and neck external lymphedema and fibrosis assessment criteria were performed to evaluate visible soft tissue edema and the degree of stiffness. Results The severity and volume of lymphedema decreased in the CDP program group (P < .05). Besides, external lymphedema and fibrosis at submental region were decreased in both CDP program and home program groups (P < .05). Conclusions While the benefits of home program are limited, a CDP program may be more effective in the management of lymphedema and fibrosis in patients diagnosed with head and neck cancer. The clinical trial registration number: NCT04286698, date: 02/25/2020, retrospectively registered. Level of Evidence 4 Laryngoscope, 2020Öğe Levels of oxidative stress, selenium and zinc, and health-related quality of life in healthy males before and after COVID-19 vaccination(Dustri-Verlag Dr Karl Feistle, 2024) Özdemir, Kadirhan; Saruhan, Ercan; Benli, Tuba Kaya; Kaya, Gozde; Cil, Zafer; Yavuz, Melike Yuksel; Meral, Orhan; Kavak, ServetObjective: The aim of this study was to determine the changes in oxidative stress, selenium (Se) and zinc (Zn), and health-related quality of life (HRQoL) following COVID-19 vaccination. Materials and methods: 20 healthy male subjects received 2 doses of inactivated COVID-19 vaccines between January and August 2021. Peripheral blood samples were taken immediately before the 1 st dose and 3 days after the 2 nd dose of the vaccine. The oxidant status (malondialdehyde (MDA) and total oxidant status (TOS)), antioxidant status (superoxide dismutase (SOD) and total antioxidant status (TAS)), Se and Zn, and HRQoL levels of the subjects were evaluated. In addition, oxidative stress index (OSI) was calculated. Results: The mean age and body mass index of the subjects were 45.85 +/- 6.38 years and 28.53 +/- 4.50 kg/m(2), respectively. Following COVID-19 vaccinations, TAS levels decreased (p = 0.004); however, SOD levels increased (p = 0.012) significantly. In addition, there were no significant changes in TOS and MDA levels (p > 0.05). Moreover, OSI showed no significant differences (p > 0.05). After the vaccination process, Se and Zn increased; however, the differences were insignificant (p > 0.05). In addition, the HRQoL of the subjects did not change (p > 0.05). Conclusion: Although the antioxidant status decreased after 2 doses of COVID-19 vaccination, the oxidant status and the oxidative stress levels of the subjects remained stable. Thus, 2 doses of inactivated COVID-19 vaccination may have no effects on oxidative stress levels in healthy males. In addition, there were no changes in the serum concentrations of Se and Zn. Moreover, there was no difference in the HRQoL of the subjects. Therefore, COVID-19 vaccination process may not affect serum Se and Zn levels and HRQoL in healthy males.Öğe The reliability, validityand cross-cultural adaptation of Turkish version of jefferson scale of empathy for health professions students(Marmara Univ, Inst Health Sciences, 2024) İsmailoğlu, Elif Günay; Özdemir, Kadirhan; Tuğral, Alper; Bakar, YeşimObjective: The study is aimed to study for the reliability, validity, and cross-cultural adaptation of the Turkish version of the Jefferson Scale of Empathy for undergraduate health profession students (JSE-HPS). Methods: Cultural adaptation of JSE-HPS was carried out in 5 stages according to the protocol of Beaton et al.JSE-HPS was administered to students who educated in the departments of Physiotherapy and Rehabilitation, Nursing and Health Management. The reliability of JSE-HPS was evaluated by internal consistency and test -retest analysis using Cronbach's alpha and intraclass correlation coefficient (ICC), respectively. Criterion validity assessed by comparing the scores of JSE-HPS and Emphatic Tendency Scale (ETS). An analysis of construct validity was carried out by exploratory and confirmatory factor analysis. Results: The exploratory factor analysis revealed the presence of three factors that explain 44.68% of the total variance and that correspond to the dimensions of the original scale. Following factor structures were obtained as Perspective taking, Compassionate care and Standing in patient's shoes. Turkish version of JSE-HPS total score were significantly correlated with the ETS total score (r=0.187, p=.005). The Cronbach's Alpha internal consistency coefficient was found alpha = .793. The test -retest reliability coefficient was 0.86. The confirmatory factor analysis verified a good fit of the model (chi 2/df = 1.776). Conclusion: The Turkish version of JSE-HPS is a valid and reliable scale for evaluating empathy levels of undergraduate health professions students.Öğe Two-particle azimuthal correlations in ?p interactions using pPb collisions at ?sNN=8.16 TeV(Elsevier, 2023) Tumasyan, A.; Adam, W.; Bergauer, T.; Dragicevic, M.; Del Valle, A. Escalante; Fruehwirth, R.; The ATLAS collaboration; Özdemir, KadirhanThe first measurements of the Fourier coefficients (V-n Delta) of the azimuthal distributions of charged hadrons emitted from photon-proton (gamma p) interactions are presented. The data are extracted from 68.8nb(-1) of ultra-peripheral proton-lead (pPb) collisions at root s(NN)= 8.16 TeV using the CMS detector. The high energy lead ions produce a flux of photons that can interact with the oncoming proton. This gamma p system provides a set of unique initial conditions with multiplicity lower than in photon-lead collisions but comparable to recent electron-positron and electron-proton data. The V-n Delta coefficients are presented in ranges of event multiplicity and transverse momentum (p(T)) and are compared to corresponding hadronic minimum bias pPb results. For a given multiplicity range, the mean p(T) of charged particles is smaller in gamma p than in pPb collisions. For both the gamma p and pPb samples, V-1 Delta is negative, V-2 Delta is positive, and V-3 Delta consistent with 0. For each multiplicity and p(T) range, V-2 Delta is larger for gamma p events. The gamma p data are consistent with model predictions that have no collective effects. (c) 2023 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). Funded by SCOAP(3).
